ID   YMQ1_CAEEL              Reviewed;         526 AA.
AC   P34492; O61223; Q95QD2;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 4.
DT   03-AUG-2022, entry version 139.
DE   RecName: Full=Putative NipSnap protein K02D10.1;
GN   ORFNames=K02D10.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 296-526 (ISOFORMS A AND B).
RX   PubMed=9661659; DOI=10.1016/s0378-1119(98)00098-5;
RA   Seroussi E., Pan H.Q., Kedra D., Roe B.A., Dumanski J.P.;
RT   "Characterization of the human NIPSNAP1 gene from 22q12: a member of a
RT   novel gene family.";
RL   Gene 212:13-20(1998).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=a;
CC         IsoId=P34492-1; Sequence=Displayed;
CC       Name=b;
CC         IsoId=P34492-2; Sequence=VSP_008868, VSP_016111;
CC   -!- SIMILARITY: Belongs to the NipSnap family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO081469; CCD71825.1; -; Genomic_DNA.
DR   EMBL; FO081469; CCD71826.1; -; Genomic_DNA.
DR   EMBL; AJ001262; CAA04636.1; -; mRNA.
DR   PIR; S44837; S44837.
DR   RefSeq; NP_498936.1; NM_066535.6.
DR   RefSeq; NP_498939.3; NM_066538.3. [P34492-1]
DR   AlphaFoldDB; P34492; -.
DR   SMR; P34492; -.
DR   BioGRID; 41435; 1.
DR   STRING; 6239.K02D10.1a; -.
DR   EPD; P34492; -.
DR   PaxDb; P34492; -.
DR   PeptideAtlas; P34492; -.
DR   EnsemblMetazoa; K02D10.1a.1; K02D10.1a.1; WBGene00019301. [P34492-1]
DR   EnsemblMetazoa; K02D10.1b.1; K02D10.1b.1; WBGene00019301. [P34492-2]
DR   GeneID; 176232; -.
DR   UCSC; K02D10.1b.1; c. elegans. [P34492-1]
DR   CTD; 176232; -.
DR   WormBase; K02D10.1a; CE17151; WBGene00019301; -. [P34492-1]
DR   WormBase; K02D10.1b; CE29423; WBGene00019301; -. [P34492-2]
DR   eggNOG; KOG2882; Eukaryota.
DR   eggNOG; KOG2883; Eukaryota.
DR   GeneTree; ENSGT00950000183018; -.
DR   HOGENOM; CLU_519950_0_0_1; -.
DR   InParanoid; P34492; -.
DR   OrthoDB; 1141024at2759; -.
DR   PhylomeDB; P34492; -.
DR   Reactome; R-CEL-9013407; RHOH GTPase cycle.
DR   PRO; PR:P34492; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00019301; Expressed in larva and 4 other tissues.
DR   ExpressionAtlas; P34492; baseline and differential.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1000; -; 2.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006357; HAD-SF_hydro_IIA.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR012577; NIPSNAP.
DR   InterPro; IPR006349; PGP_euk.
DR   Pfam; PF13344; Hydrolase_6; 1.
DR   Pfam; PF07978; NIPSNAP; 1.
DR   SUPFAM; SSF54909; SSF54909; 2.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR01460; HAD-SF-IIA; 1.
DR   TIGRFAMs; TIGR01452; PGP_euk; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..526
FT                   /note="Putative NipSnap protein K02D10.1"
FT                   /id="PRO_0000221156"
FT   VAR_SEQ         1..237
FT                   /note="Missing (in isoform b)"
FT                   /evidence="ECO:0000303|PubMed:9661659"
FT                   /id="VSP_008868"
FT   VAR_SEQ         238..260
FT                   /note="DPKRTVMFGDRLDTDIMFGNANG -> MNRSGQRLIVSAPRQIAFSTAVR
FT                   (in isoform b)"
FT                   /evidence="ECO:0000303|PubMed:9661659"
FT                   /id="VSP_016111"
SQ   SEQUENCE   526 AA;  59049 MW;  31F5685B512482F8 CRC64;
     MSINRISKNE LLANYDTFLF DADGVLWTGD IPVPGAIEWI NLLLEDPSKK VFVLTNNSTK
     TLEQYMKKIE KLGFGHLGRN NVISPAIVLA DYLKSNADKF SGEYVYLIGT ENLKATLEND
     GGVKCFGTGP DSIRDHTDGD FIHKVDMSIA PKAVVCSYDA HFSYPKIMKA SNYLQDPSVE
     YLVTNQDYTF PGPVPGVVIP GSGATSAAVT AVTGRDPKVF GKPHKPMADF LLRRAHVDPK
     RTVMFGDRLD TDIMFGNANG QLSATPIQCQ NESENSEPQK QGWISRLLKG QSMDPSSWQK
     QSHSSLLSNS ELMYEFMTHN YRPGEQDAYL DAFGKYKNEM NQKNPSIELV GSWTCAYGRT
     RDQAIHLWRH NKGYEDVDSS ISLHGKDSGI RAADNDVAKL CGRRKNLIVK SFSYWREPEQ
     RPPNHVYDLR SYVLQPGTMI DWASAWAKGI QYRREANQDV GGFFAQVGQL YVVYHIWAYP
     SMSGRNDTRH ATWAKPGWDA TVANTVPLIK KMQSKILTPT KYSQLE