CBP2_SACPA
ID CBP2_SACPA Reviewed; 630 AA.
AC Q08996;
DT 09-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 46.
DE RecName: Full=Cytochrome B pre-mRNA-processing protein 2;
GN Name=CBP2;
OS Saccharomyces paradoxus (Yeast) (Saccharomyces douglasii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=27291;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8602146; DOI=10.1007/bf02174389;
RA Li G.Y., Tian G.L., Slonimski P.P., Herbert C.J.;
RT "The CBP2 gene from Saccharomyces douglasii is a functional homologue of
RT the Saccharomyces cerevisiae gene and is essential for respiratory growth
RT in the presence of a wild-type (intron containing) mitochondrial genome.";
RL Mol. Gen. Genet. 250:316-322(1996).
CC -!- FUNCTION: Appears to be specifically required for the splicing of the
CC terminal intron (bI5) of the cytochrome b pre-mRNA. Can also stimulates
CC the splicing of the omega intron of the precursor of large ribosomal
CC RNA (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
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DR EMBL; X94370; CAA64148.1; -; Genomic_DNA.
DR AlphaFoldDB; Q08996; -.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0000372; P:Group I intron splicing; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR016424; Cbp2.
DR PIRSF; PIRSF004611; CBP2; 1.
PE 3: Inferred from homology;
KW Mitochondrion; mRNA processing; mRNA splicing.
FT CHAIN 1..630
FT /note="Cytochrome B pre-mRNA-processing protein 2"
FT /id="PRO_0000089379"
SQ SEQUENCE 630 AA; 73725 MW; D26C67CF27865F28 CRC64;
MVNWQTLFMV SLRRQGSSSR YRYKFNMENI THQVFPRCKQ AFKKANLSYE YCDLEGKLYN
ASLMDLQKML LRDINAPRDH VFKIVRTDLV EKSSKKRIQH WEQIAPIFDH PLSLYENLLS
EMDNDFKPSF EWQQLIEVRS RDDQLKLQRV VWPKSIFSNF CRGIGVKKNT YDRLLKQNNG
EVPMFVNPAN AKPLPLFQVG DDATIGEFDG IGIFPYFVVK HRAFFVTEVD KLKTKIISPL
CNLNERKRTD KANAGRLLEN EKGEPFYVDA KGAASRAADG NAVTLKQLLE RSVSHKTLWS
KQTNKDRTCP GDILRATILS NDFSIRQLRT EFCKNFILYN IFTILQRNKK SIRDFSNDNN
VPSFRFNWNV WDSYIWKQYQ EAESMTLPAD QASLINYKTK YDSFLQDLQT YSTLVISEMK
WNQFSIFQNN ETSLSRFEHI TLILQTILTK SKMIRIFQPN LYKFMQDDLR ATLMELTGFT
ESINATIGPG FANEQSLQSA NALKKLANQL LHFEQKIYAE KFRVNRPIQL RPLTLSTNFK
IVILDKQNAI PEIFQTLLKF TTQITTYFVK DLSEVELHGH MHCIDKKMLD KSTFMYLYEL
KYNEDLKAVP PQKEKIVDNI IGLLSNDEEH