YN02_CAEEL
ID YN02_CAEEL Reviewed; 719 AA.
AC Q03606; Q03608; Q2EEP6; Q2EEP7;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 3.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=CRAL-TRIO domain-containing protein T23G5.2;
GN ORFNames=T23G5.2;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=7906398; DOI=10.1038/368032a0;
RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA Wilkinson-Sproat J., Wohldman P.;
RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT elegans.";
RL Nature 368:32-38(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=a;
CC IsoId=Q03606-1; Sequence=Displayed;
CC Name=b;
CC IsoId=Q03606-2; Sequence=VSP_019769, VSP_019770;
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DR EMBL; Z19158; CAJ76964.1; -; Genomic_DNA.
DR EMBL; Z19158; CAJ76965.1; -; Genomic_DNA.
DR PIR; B88551; B88551.
DR PIR; S28303; S28303.
DR PIR; S28305; S28305.
DR RefSeq; NP_001040875.1; NM_001047410.4. [Q03606-1]
DR RefSeq; NP_001040876.1; NM_001047411.2. [Q03606-2]
DR AlphaFoldDB; Q03606; -.
DR SMR; Q03606; -.
DR BioGRID; 41501; 1.
DR STRING; 6239.T23G5.2a.1; -.
DR iPTMnet; Q03606; -.
DR EPD; Q03606; -.
DR PaxDb; Q03606; -.
DR PeptideAtlas; Q03606; -.
DR PRIDE; Q03606; -.
DR EnsemblMetazoa; T23G5.2a.1; T23G5.2a.1; WBGene00011962. [Q03606-1]
DR EnsemblMetazoa; T23G5.2b.1; T23G5.2b.1; WBGene00011962. [Q03606-2]
DR GeneID; 176302; -.
DR KEGG; cel:CELE_T23G5.2; -.
DR UCSC; T23G5.2a.1; c. elegans. [Q03606-1]
DR CTD; 176302; -.
DR WormBase; T23G5.2a; CE39782; WBGene00011962; -. [Q03606-1]
DR WormBase; T23G5.2b; CE39783; WBGene00011962; -. [Q03606-2]
DR eggNOG; KOG1471; Eukaryota.
DR GeneTree; ENSGT00940000168605; -.
DR HOGENOM; CLU_023840_0_0_1; -.
DR InParanoid; Q03606; -.
DR OMA; NAEWTCF; -.
DR OrthoDB; 1133487at2759; -.
DR PhylomeDB; Q03606; -.
DR PRO; PR:Q03606; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00011962; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; -; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011074; CRAL/TRIO_N_dom.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR InterPro; IPR006797; PRELI/MSF1_dom.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF03765; CRAL_TRIO_N; 1.
DR Pfam; PF04707; PRELI; 1.
DR SMART; SM01100; CRAL_TRIO_N; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF101576; SSF101576; 1.
DR SUPFAM; SSF46938; SSF46938; 1.
DR SUPFAM; SSF52087; SSF52087; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50866; GOLD; 1.
DR PROSITE; PS50904; PRELI_MSF1; 1.
PE 4: Predicted;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..719
FT /note="CRAL-TRIO domain-containing protein T23G5.2"
FT /id="PRO_0000210751"
FT DOMAIN 2..175
FT /note="PRELI/MSF1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00158"
FT DOMAIN 319..495
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
FT DOMAIN 524..681
FT /note="GOLD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00096"
FT REGION 700..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 235..237
FT /note="ADS -> GAL (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_019769"
FT VAR_SEQ 238..719
FT /note="Missing (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_019770"
SQ SEQUENCE 719 AA; 81082 MW; 468A4AA265AACD9B CRC64;
MVQTYRSPVR IYKHPFEIVM AAYEMRFPTC PQIPIFVGSE VTYEYKSVDG AEWVIDRKCQ
LNVEAPYLVK KIAGVDYVYF SQKNSLDRRK RTLDIEATNI SFSSRINVKE NCTYYVHAEN
ENWTCFEQSA SLDVKNFFGL ESAVEKLAVR QYGANLAKGK EILEFFIEEL LKKTTHIERF
RDADQEETTS ATDSAIEMKE LSDGDAVLVN DRPPMLAAET DEMRTARATA SFDDADSKLE
AEYIRRFLGQ LSPLEESRLC EIKYSLQAHH KGKLPNDAHL LRFLRARDFD VAKAKDMVHA
SIIWRKQHNV DKILEEWTRP TVIKQYFPGC WHNSDKAGRP MYILRFGQLD TKGMLRSCGV
ENLVKLTLSI CEDGLQRAAE ATRKLGTPIS SWSLVVDLDG LSMRHLWRPG VQCLLKIIEI
VEANYPETMG QVLVVRAPRV FPVLWTLISP FIDEKTRKKF MVSGGSGGDL KEELRKHIEE
KFIPDFLGGS CLTTNCGLGG HVPKSMYLPV EEQEGASSSE DPLHSTYTST ATWRGYPVEV
VIPIETAGCV LTWDFDVLKN DCEFSLYFST EKIEQPAVRD GAQSPTTILN PVEMVSAAIG
GASHQHPDLQ CAPELKIGTP QLRLEEKAVV FQEGDSMQGS HYCSRAGTYI MQWRVPETAA
GHSSTFDFGS HKCRLIYYYE ILNSENFRGS VASLESCRSS SFSSIAPPTP PTPGTPRNP
