ID   CBP3_MOROL              Reviewed;          22 AA.
AC   P86528;
DT   15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT   15-JUN-2010, sequence version 1.
DT   25-MAY-2022, entry version 11.
DE   RecName: Full=Chitin-binding protein 3 {ECO:0000303|PubMed:23193603};
DE            Short=Mo-CBP3 {ECO:0000303|PubMed:23193603};
DE   Flags: Fragment;
OS   Moringa oleifera (Horseradish tree) (Moringa pterygosperma).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Moringaceae; Moringa.
OX   NCBI_TaxID=3735;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, AND GLYCOSYLATION.
RC   TISSUE=Seed;
RX   PubMed=23193603; DOI=10.1002/bip.22068;
RA   Gifoni J.M., Oliveira J.T., Oliveira H.D., Batista A.B., Pereira M.L.,
RA   Gomes A.S., Oliveira H.P., Grangeiro T.B., Vasconcelos I.M.;
RT   "A novel chitin-binding protein from Moringa oleifera seed with potential
RT   for plant disease control.";
RL   Biopolymers 98:406-415(2012).
RN   [2]
RP   FUNCTION.
RX   PubMed=28634471; DOI=10.3389/fmicb.2017.00980;
RA   Neto J.X.S., Pereira M.L., Oliveira J.T.A., Rocha-Bezerra L.C.B.,
RA   Lopes T.D.P., Costa H.P.S., Sousa D.O.B., Rocha B.A.M., Grangeiro T.B.,
RA   Freire J.E.C., Monteiro-Moreira A.C.O., Lobo M.D.P., Brilhante R.S.N.,
RA   Vasconcelos I.M.;
RT   "A Chitin-binding Protein Purified from Moringa oleifera Seeds Presents
RT   Anticandidal Activity by Increasing Cell Membrane Permeability and Reactive
RT   Oxygen Species Production.";
RL   Front. Microbiol. 8:980-980(2017).
CC   -!- FUNCTION: Chitin-binding protein (PubMed:23193603). Has antifungal
CC       activity against F.solani, F.oxysporum, C.musae and C.gloesporoides but
CC       not against P.oligandrum (PubMed:23193603). Depending on concentration
CC       the antifungal activity can be fungistatic or fungicidal
CC       (PubMed:23193603). Inhibits both spore germination and mycelial growth
CC       in F.solani at a concentration of 0.1 mg/ml (PubMed:23193603). Has
CC       antifungal activity against C.krusei, C.albicans, C.tropicalis and
CC       C.parapsilosis (PubMed:28634471). Has no chitinase, beta-glucanase or
CC       hemagglutinating activity (PubMed:23193603). Acts as a flocculent
CC       (PubMed:23193603). {ECO:0000269|PubMed:23193603,
CC       ECO:0000269|PubMed:28634471}.
CC   -!- PTM: Glycosylated; contains 2.5% carbohydrates.
CC       {ECO:0000269|PubMed:23193603}.
CC   -!- MISCELLANEOUS: On the 2D-gel the determined pI of this protein is:
CC       10.8, its MW is: 14.34 kDa.
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DR   AlphaFoldDB; P86528; -.
DR   GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IDA:UniProtKB.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antimicrobial; Chitin-binding; Direct protein sequencing; Fungicide.
FT   CHAIN           1..>22
FT                   /note="Chitin-binding protein 3"
FT                   /id="PRO_0000394695"
FT   NON_TER         22
SQ   SEQUENCE   22 AA;  2562 MW;  608826BBAAD9C13B CRC64;
     CPAIQRCCQQ LRNIQPPCRC CQ