ID   YN25_SCHPO              Reviewed;         762 AA.
AC   O59741; Q9UU51;
DT   16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 2.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=Uncharacterized transcriptional regulatory protein C530.05;
GN   ORFNames=SPBC530.05;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   REVISION OF GENE MODEL.
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 20-90, AND SUBCELLULAR
RP   LOCATION.
RC   STRAIN=ATCC 38364 / 968;
RX   PubMed=10759889; DOI=10.1046/j.1365-2443.2000.00317.x;
RA   Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T.,
RA   Hiraoka Y.;
RT   "Large-scale screening of intracellular protein localization in living
RT   fission yeast cells by the use of a GFP-fusion genomic DNA library.";
RL   Genes Cells 5:169-190(2000).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227,
CC       ECO:0000269|PubMed:10759889}.
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DR   EMBL; CU329671; CAA19171.2; -; Genomic_DNA.
DR   EMBL; AB027808; BAA87112.1; -; Genomic_DNA.
DR   PIR; T40521; T40521.
DR   RefSeq; NP_595318.2; NM_001021225.2.
DR   AlphaFoldDB; O59741; -.
DR   SMR; O59741; -.
DR   BioGRID; 277419; 22.
DR   STRING; 4896.SPBC530.05.1; -.
DR   iPTMnet; O59741; -.
DR   MaxQB; O59741; -.
DR   PaxDb; O59741; -.
DR   PRIDE; O59741; -.
DR   EnsemblFungi; SPBC530.05.1; SPBC530.05.1:pep; SPBC530.05.
DR   GeneID; 2540903; -.
DR   KEGG; spo:SPBC530.05; -.
DR   PomBase; SPBC530.05; -.
DR   VEuPathDB; FungiDB:SPBC530.05; -.
DR   eggNOG; ENOG502QZJZ; Eukaryota.
DR   HOGENOM; CLU_369248_0_0_1; -.
DR   InParanoid; O59741; -.
DR   OMA; IWSERES; -.
DR   PRO; PR:O59741; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; NAS:PomBase.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR   GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR   GO; GO:1901522; P:positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; IMP:PomBase.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR007219; Transcription_factor_dom_fun.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF04082; Fungal_trans; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00906; Fungal_trans; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..762
FT                   /note="Uncharacterized transcriptional regulatory protein
FT                   C530.05"
FT                   /id="PRO_0000115013"
FT   DNA_BIND        30..57
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          647..668
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        648..668
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   762 AA;  85199 MW;  8CAA1CB7267CB535 CRC64;
     MENLKSASPE EDSPRHGDNM GKPKRIPRAC DMCRKRKIRC DGKQPACSNC VSHGIPCVFT
     ARPKRRTGQR QMYIKSLVSR LEQMESTLRS VIPNYDQQPD IIHPSSTPKN YHDLNCTKGE
     TSSDDSTDDI AFLNEKMGTL VTTPIGSQKY FGSSSTFSII QHAAKFASGV ESDKVLEHLS
     MAKSGCLFDP DESFDGSKAE LPSSEIANIY IDAYFKSYNP LFPVFTRENF YQKFGSPNCF
     KKPDGSIDLV NYASYVVVLS LGCLAIADTE EQVSRANALF KNTLGISIEV TKDMSFRTLV
     FNFLTSVYYC AVSKPNAVWL NVGVVVRVAQ TLGLHRNSAM WSIGKEDAEE KARLFWYIYY
     LDRVSSMMTG KPVAFQDDDI DQMVPFYSIY CYYGLKPPEG DPLGTFNFLE AEVQLTRIVG
     QVLKELYSVS GMKSNSSQVM EKILEFDLLL NNWYNSLPDC MQPRNRFKIP KFCSSNLILT
     SAIYYSCLIL IHRHSLTKNL QVNCVHRGTG SITDSQALCI AAARSITNLF VESVDLQPLI
     MKIIMYHAFT SSIIIFISIL KRPLASICSE DLNCLISVKN RLISFETHGF VRLNVVMDAL
     ESMISTAQAA MQKAKQIAIN FSSNLATNED VTNSGMPDIA DVSLKSQSHV PPRISSNHSD
     TSVKSNSPSS IFDNSGYLNS LNNSILQMHQ NLQNSSNTND QYKFDSVQEN ELHANITPVL
     DQTMSMFPFK DQLDLNFAAA NVYNPNVFDD MGLDCSFYGN GL