ID   YN28_SCHPO              Reviewed;         815 AA.
AC   O59744;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Uncharacterized transcriptional regulatory protein C530.08;
GN   ORFNames=SPBC530.08;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       membrane {ECO:0000255|PROSITE-ProRule:PRU00227,
CC       ECO:0000269|PubMed:16823372}; Single-pass membrane protein
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329671; CAA19174.1; -; Genomic_DNA.
DR   PIR; T40524; T40524.
DR   RefSeq; NP_595321.1; NM_001021228.2.
DR   AlphaFoldDB; O59744; -.
DR   SMR; O59744; -.
DR   BioGRID; 276790; 2.
DR   STRING; 4896.SPBC530.08.1; -.
DR   iPTMnet; O59744; -.
DR   MaxQB; O59744; -.
DR   PaxDb; O59744; -.
DR   PRIDE; O59744; -.
DR   EnsemblFungi; SPBC530.08.1; SPBC530.08.1:pep; SPBC530.08.
DR   GeneID; 2540259; -.
DR   KEGG; spo:SPBC530.08; -.
DR   PomBase; SPBC530.08; -.
DR   VEuPathDB; FungiDB:SPBC530.08; -.
DR   eggNOG; ENOG502QSY2; Eukaryota.
DR   HOGENOM; CLU_373452_0_0_1; -.
DR   InParanoid; O59744; -.
DR   OMA; YYFHFAN; -.
DR   PhylomeDB; O59744; -.
DR   PRO; PR:O59744; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; ISM:PomBase.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; NAS:PomBase.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR   GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; NAS:PomBase.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR007219; Transcription_factor_dom_fun.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF04082; Fungal_trans; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00906; Fungal_trans; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Membrane; Metal-binding; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation; Transmembrane;
KW   Transmembrane helix; Zinc.
FT   CHAIN           1..815
FT                   /note="Uncharacterized transcriptional regulatory protein
FT                   C530.08"
FT                   /id="PRO_0000310391"
FT   TRANSMEM        560..580
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DNA_BIND        31..57
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          646..668
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          769..792
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        777..792
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   815 AA;  93538 MW;  174A8A711C467115 CRC64;
     MDNESHSQET ESKILEGAKV ATRRRRVTRA CDMCRRKKIK CDGLRPCKNC KAGKLECTYH
     MPSSRKSSFS PEYVENLESR VRYLETLLKK NTNFDLSSNS PSFLFFLREQ KFQATNELEN
     MSPERKVIFT SMINYGNLFV DAKHGTRYFR GGSSIHVLIQ HLIRRLPGDF EICEPYSAYP
     LGNKNIQFDD NDPEYQFFTP TPRFSIDFMV SSVDPREIQL PGIEEALCIT KAAVSYVSGI
     VFYTTYADFP KKIRLLYSGN YQGNFFPLFL SILCVGYYHH LLNNPSNTEL QSLIKKYSFY
     SERLVKSADN FTIESIQCLL ILSIYRYCRT EISAAWYYMK LGLNCCLRLG LHRNITEGFT
     EEQIDSRRRI FWAIYCYDRQ LCTLFGFPLG VRDEDIDQCL PVTPKFPSVT EIEANARLFF
     FHGVKLYKIS SRILTKLYSP NSRNVTKKHI SYAVIQDLEQ LLDGFYNSLP RVFRAEQPGE
     FQANHFFYNL QLVYYSFRML IYRPLLHYLE ADSPAMQALK VPDRQTAFTL ACKCVDSAIV
     CVQNLSHLSK GLKRTLDRYY WTTVYCGFST IVTLIFAALL TKNTNLLIHI SVARESIEAL
     AHECVTRRLL PLIDKMRESL MKILESNADG YKQMSPTKAP QVFESESNVP INNGPQQSID
     KESNSNTQLP QVETEGQQQS VFDGNIGTIP YQAYNMNEDS FIDINTLSSM LNYHTQAVSI
     HHPSFYISRS DVPLEEEFQI PNELLAVDPV AESMQENSDI INEAFGLVDP DVSDGKSRES
     SSLNNSTPFN PTVNIDPASI LEHFSQNVMK DSQNS