ID   YN41_SCHPO              Reviewed;         580 AA.
AC   O59698; Q9UU38;
DT   29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Uncharacterized transporter C36.01c;
GN   ORFNames=SPBC36.01c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 241-344, AND SUBCELLULAR
RP   LOCATION.
RC   STRAIN=ATCC 38364 / 968;
RX   PubMed=10759889; DOI=10.1046/j.1365-2443.2000.00317.x;
RA   Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T.,
RA   Hiraoka Y.;
RT   "Large-scale screening of intracellular protein localization in living
RT   fission yeast cells by the use of a GFP-fusion genomic DNA library.";
RL   Genes Cells 5:169-190(2000).
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-99, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:10759889}; Multi-
CC       pass membrane protein {ECO:0000269|PubMed:10759889}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. CAR1 family.
CC       {ECO:0000305}.
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DR   EMBL; CU329671; CAA19049.1; -; Genomic_DNA.
DR   EMBL; AB027835; BAA87139.1; -; Genomic_DNA.
DR   PIR; T40296; T40296.
DR   RefSeq; NP_595329.1; NM_001021237.2.
DR   AlphaFoldDB; O59698; -.
DR   BioGRID; 277450; 2.
DR   STRING; 4896.SPBC36.01c.1; -.
DR   iPTMnet; O59698; -.
DR   PaxDb; O59698; -.
DR   PRIDE; O59698; -.
DR   EnsemblFungi; SPBC36.01c.1; SPBC36.01c.1:pep; SPBC36.01c.
DR   GeneID; 2540934; -.
DR   KEGG; spo:SPBC36.01c; -.
DR   PomBase; SPBC36.01c; -.
DR   VEuPathDB; FungiDB:SPBC36.01c; -.
DR   eggNOG; KOG0255; Eukaryota.
DR   HOGENOM; CLU_008455_11_6_1; -.
DR   InParanoid; O59698; -.
DR   PhylomeDB; O59698; -.
DR   PRO; PR:O59698; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; ISO:PomBase.
DR   GO; GO:0015606; F:spermidine transmembrane transporter activity; ISO:PomBase.
DR   GO; GO:0000297; F:spermine transmembrane transporter activity; ISO:PomBase.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:1903711; P:spermidine transmembrane transport; IC:PomBase.
DR   GO; GO:1903710; P:spermine transmembrane transport; IC:PomBase.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   1: Evidence at protein level;
KW   Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..580
FT                   /note="Uncharacterized transporter C36.01c"
FT                   /id="PRO_0000173448"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        265..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        295..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        405..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        450..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        476..496
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        511..533
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        546..566
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         99
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   580 AA;  64184 MW;  935E6351785D612E CRC64;
     MSESSVNADT PKNTNDVLNG AYQSATTEPE GQYRSATDNP SLYQVPTHGS LYRNLSNSAS
     AYYPANGNMN SREPANELSD ISSLAEKGEL EPPMAKLLSD PDFQGKQFPT VEAPELFIFE
     LAPDSPSIAL NWTFWRKMKT TSIYAYASLT IAWGSSVLSP ASATLAKKYH IGMTTSLLNV
     SLFMLGYCLG PICWAPMSEI TGRKTPLYIG LFLFSVFQIA VATAQDIQTI MICRFFGGYG
     ACVPLCVVAA AFADMYPNRY RGTAITIFAA VIFVGPLVAP IVGGFLTKSY LGWRWTEYIT
     SFMGFLSIIL IYLFCEETYL KTITENKVQE YREITGNQLV HARSEEESLS ARDIIMNYLL
     IPLKMLATEP IVFLVSLYCS FVYAIIYLLL EAYPVIFQEG RHFPLGVSAL PYIGILVGVF
     IGCGINCLFE PWYFRQVIKA GNKPAPEARL PPMMIGSFLF PAGIFWLAWS GYYTYVHWIV
     PTLSGLLTGA GILLIFLQCL NYLLDAYLFR AASVFAANVI MRSAVAGGFP LFAVQMFHNM
     GVGWAGSLLG FIATALIPMP FAFFFFGKKI RAKSKMTAQF