CBP3_WHEAT
ID CBP3_WHEAT Reviewed; 500 AA.
AC P11515;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1989, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Serine carboxypeptidase 3;
DE EC=3.4.16.5;
DE AltName: Full=CP-WIII;
DE AltName: Full=Serine carboxypeptidase III;
DE Flags: Precursor;
GN Name=CBP3;
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2820978; DOI=10.1016/s0021-9258(19)76487-4;
RA Baulcombe D.C., Barker R.F., Jarvis M.G.;
RT "A gibberellin responsive wheat gene has homology to yeast carboxypeptidase
RT Y.";
RL J. Biol. Chem. 262:13726-13735(1987).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Release of a C-terminal amino acid with broad specificity.;
CC EC=3.4.16.5; Evidence={ECO:0000255|PROSITE-ProRule:PRU10074,
CC ECO:0000255|PROSITE-ProRule:PRU10075};
CC -!- SUBUNIT: Monomer. {ECO:0000305}.
CC -!- INDUCTION: By gibberellic acid (GA).
CC -!- SIMILARITY: Belongs to the peptidase S10 family. {ECO:0000305}.
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DR EMBL; J02817; AAA34273.1; -; Genomic_DNA.
DR PIR; A29412; A29412.
DR AlphaFoldDB; P11515; -.
DR SMR; P11515; -.
DR STRING; 4565.Traes_6AS_E1707A5FA.1; -.
DR ESTHER; wheat-cbp3; Carboxypeptidase_S10.
DR MEROPS; S10.009; -.
DR PRIDE; P11515; -.
DR eggNOG; KOG1282; Eukaryota.
DR Proteomes; UP000019116; Unplaced.
DR ExpressionAtlas; P11515; baseline.
DR GO; GO:0005773; C:vacuole; IBA:GO_Central.
DR GO; GO:0004185; F:serine-type carboxypeptidase activity; IBA:GO_Central.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; -; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001563; Peptidase_S10.
DR InterPro; IPR033124; Ser_caboxypep_his_AS.
DR InterPro; IPR018202; Ser_caboxypep_ser_AS.
DR PANTHER; PTHR11802; PTHR11802; 1.
DR Pfam; PF00450; Peptidase_S10; 1.
DR PRINTS; PR00724; CRBOXYPTASEC.
DR SUPFAM; SSF53474; SSF53474; 1.
DR PROSITE; PS00560; CARBOXYPEPT_SER_HIS; 1.
DR PROSITE; PS00131; CARBOXYPEPT_SER_SER; 1.
PE 2: Evidence at transcript level;
KW Carboxypeptidase; Disulfide bond; Glycoprotein; Hydrolase; Protease;
KW Reference proteome; Signal; Zymogen.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT PROPEP 22..73
FT /evidence="ECO:0000250"
FT /id="PRO_0000004330"
FT CHAIN 74..484
FT /note="Serine carboxypeptidase 3"
FT /id="PRO_0000004331"
FT PROPEP 485..500
FT /evidence="ECO:0000250"
FT /id="PRO_0000004332"
FT ACT_SITE 216
FT /evidence="ECO:0000250"
FT ACT_SITE 404
FT /evidence="ECO:0000250"
FT ACT_SITE 461
FT /evidence="ECO:0000250"
FT BINDING 407
FT /ligand="substrate"
FT /evidence="ECO:0000250"
FT CARBOHYD 144
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 126..366
FT /evidence="ECO:0000250"
FT DISULFID 294..309
FT /evidence="ECO:0000250"
FT DISULFID 332..337
FT /evidence="ECO:0000250"
SQ SEQUENCE 500 AA; 55334 MW; B2ACE10EF8484CDA CRC64;
MATTPRLASL LLLLALCAAA AGALRLPPDA SFPGAQAERL IRALNLLPGR PRRGLGAGAE
DVAPGQLLER RVTLPGLPEG VGDLGHHAGY YRLPNTHDAR MFYFFFESRG KKEDPVVIWL
TGGPGCSSEL AVFYENGPFT IANNMSLVWN KFGWDKISNI IFVDPATGTG FSYSSDDRDT
RHDEAGVSND LYDFLQVFFK KHPEFVKNDF FITGESYAGH YIPAFASRVH QGNKKNEGTH
INLKGFAIGN GLTDPAIQYK AYTDYALDMN LIQKADYDRI NKFIPPCEFA IKLCGTDGKA
SCMAAYMVCN SIFNSIMKLV GTKNYYDVRK ECEGKLCYDF SNLEKFFGDK AVRQAIGVGD
IEFVSCSTSV YQAMLTDWMR NLEVGIPALL EDGINVLIYA GEYDLICNWL GNSRWVHSME
WSGQKDFAKT AESSFLVDDA QAGVLKSHGA LSFLKVHNAG HMVPMDQPKA ALEMLRRFTQ
GKLKESVPEE EPATTFYAAI
