ID   YN8C_SCHPO              Reviewed;         205 AA.
AC   Q9P791;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Uncharacterized Nudix hydrolase P35G2.12;
DE            EC=3.6.-.-;
GN   ORFNames=SPBP35G2.12;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329671; CAB87374.1; -; Genomic_DNA.
DR   RefSeq; NP_595387.1; NM_001021294.2.
DR   AlphaFoldDB; Q9P791; -.
DR   SMR; Q9P791; -.
DR   BioGRID; 277867; 8.
DR   STRING; 4896.SPBP35G2.12.1; -.
DR   MaxQB; Q9P791; -.
DR   PaxDb; Q9P791; -.
DR   EnsemblFungi; SPBP35G2.12.1; SPBP35G2.12.1:pep; SPBP35G2.12.
DR   GeneID; 2541356; -.
DR   KEGG; spo:SPBP35G2.12; -.
DR   PomBase; SPBP35G2.12; -.
DR   VEuPathDB; FungiDB:SPBP35G2.12; -.
DR   eggNOG; KOG3041; Eukaryota.
DR   HOGENOM; CLU_062658_0_1_1; -.
DR   InParanoid; Q9P791; -.
DR   OMA; CNTNLHM; -.
DR   PhylomeDB; Q9P791; -.
DR   Reactome; R-SPO-2393930; Phosphate bond hydrolysis by NUDT proteins.
DR   PRO; PR:Q9P791; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0047631; F:ADP-ribose diphosphatase activity; ISO:PomBase.
DR   GO; GO:0006753; P:nucleoside phosphate metabolic process; IBA:GO_Central.
DR   GO; GO:0009191; P:ribonucleoside diphosphate catabolic process; IC:PomBase.
DR   GO; GO:0019693; P:ribose phosphate metabolic process; IBA:GO_Central.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR020084; NUDIX_hydrolase_CS.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   Pfam; PF00293; NUDIX; 1.
DR   SUPFAM; SSF55811; SSF55811; 1.
DR   PROSITE; PS51462; NUDIX; 1.
DR   PROSITE; PS00893; NUDIX_BOX; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Nucleus; Reference proteome.
FT   CHAIN           1..205
FT                   /note="Uncharacterized Nudix hydrolase P35G2.12"
FT                   /id="PRO_0000317227"
FT   DOMAIN          51..189
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00794"
FT   MOTIF           90..111
FT                   /note="Nudix box"
SQ   SEQUENCE   205 AA;  23032 MW;  03C141374A137CB3 CRC64;
     MSQDQKPKVL EVSNLENQDA KWTSLKKIRW QDEKGKIRFW EMAERTTRSE ANVDAVAILA
     IVPIDGSPHV LCQKQFRPPI GKFCIEIPAG LVDSKESCED AAIRELREET GYVGTVMDST
     TVMYNDPGLT NANLKIILAD IDMSKPENQN PQQQLDDGEY IENFPIKLSS LQEELFSLEK
     KGFAIDVRLS TFALGLHAGL KYLSS