YN94_YEAST
ID YN94_YEAST Reviewed; 1116 AA.
AC P53751; D6W1P0;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=Uncharacterized membrane glycoprotein YNR065C;
GN OrderedLocusNames=YNR065C; ORFNames=N3539;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169873;
RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K.,
RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K.,
RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M.,
RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F.,
RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F.,
RA Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C.,
RA Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A.,
RA Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H.,
RA Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L.,
RA Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R.,
RA Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D.,
RA Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A.,
RA Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C.,
RA Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F.,
RA Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G.,
RA Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M.,
RA Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
RT evolutionary implications.";
RL Nature 387:93-98(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; Z71680; CAA96347.1; -; Genomic_DNA.
DR EMBL; BK006947; DAA10606.1; -; Genomic_DNA.
DR PIR; S63397; S63397.
DR RefSeq; NP_014463.1; NM_001183242.1.
DR AlphaFoldDB; P53751; -.
DR SMR; P53751; -.
DR BioGRID; 35891; 36.
DR DIP; DIP-4251N; -.
DR IntAct; P53751; 7.
DR MINT; P53751; -.
DR STRING; 4932.YNR065C; -.
DR iPTMnet; P53751; -.
DR MaxQB; P53751; -.
DR PaxDb; P53751; -.
DR PRIDE; P53751; -.
DR EnsemblFungi; YNR065C_mRNA; YNR065C; YNR065C.
DR GeneID; 855802; -.
DR KEGG; sce:YNR065C; -.
DR SGD; S000005348; YNR065C.
DR VEuPathDB; FungiDB:YNR065C; -.
DR eggNOG; KOG3511; Eukaryota.
DR GeneTree; ENSGT01030000234563; -.
DR HOGENOM; CLU_000700_0_1_1; -.
DR InParanoid; P53751; -.
DR OMA; GNIFSTH; -.
DR BioCyc; YEAST:G3O-33369-MON; -.
DR PRO; PR:P53751; -.
DR Proteomes; UP000002311; Chromosome XIV.
DR RNAct; P53751; protein.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0006895; P:Golgi to endosome transport; IBA:GO_Central.
DR GO; GO:0006896; P:Golgi to vacuole transport; IBA:GO_Central.
DR GO; GO:0006892; P:post-Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006623; P:protein targeting to vacuole; IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 2.
DR InterPro; IPR031777; Sortilin_C.
DR InterPro; IPR031778; Sortilin_N.
DR InterPro; IPR006581; VPS10.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR Pfam; PF15902; Sortilin-Vps10; 2.
DR Pfam; PF15901; Sortilin_C; 2.
DR SMART; SM00602; VPS10; 1.
PE 4: Predicted;
KW Glycoprotein; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..1116
FT /note="Uncharacterized membrane glycoprotein YNR065C"
FT /id="PRO_0000203483"
FT TRANSMEM 934..957
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REPEAT 21..32
FT /note="BNR 1"
FT REPEAT 67..78
FT /note="BNR 2"
FT REPEAT 307..318
FT /note="BNR 3"
FT REPEAT 404..415
FT /note="BNR 4"
FT REPEAT 607..618
FT /note="BNR 5"
FT REPEAT 686..697
FT /note="BNR 6"
FT REPEAT 727..738
FT /note="BNR 7"
FT REGION 1069..1116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 35
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 336
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 553
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 846
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 985
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1116 AA; 125200 MW; C0361878FE4DAB90 CRC64;
MLMTGSVGDG SEFDWEDQKT FISRDGGLTW RFVHNSSGLY ATGDLGNIIV YIPYDPEEDG
DFQSEFYYSL DQGRTWNEYE LTNAISSVHP YKLINPTPDG SGSKFIFKGT FATTDSETNS
ITSLKGVEYI IDFSAAFDSR TCEEEDFEDW DLADGKCVNG AKYKYRRRKQ DAQCLVKKAF
KDLSLDETPC NSCGESDYEC SFEFVRDANG LCIPDYNLIA FSNICDKSKD KSVLVEPLQL
IKGDECKTPM KIEPVDIPCD EIPEEGSSDR EIVTTENKFD FEIKFYQYFD TVADESLVML
NSIGDAYISH DGGQTIKRFD TNGEKIVEVV FNPYFNSSAY LFGSKGNIFS THDRGHSFMI
AKLPEARQLG MPLDFSAKAQ DTFIYYGGKN CESILSPECH AVAYLTKDGG ETFTEMLDNA
IHCEFAGTLF EYPSNEEMVM CQVKKKSSET RSLVSSIDFF QGDNKIIFEN IIGYLSTGGY
IIVAVPHEDN ELRAYVTIDG TEFAEAKFPY GQDVSKQEAF TILGSEKGSI FLHLATNLES
GHDFGNLLKS NSNGTSFVTL EHAVNRNTFG YVDFEKVQGL EGIIITNIVS NREKVGENKE
DEQLKTKITF NDGSDWNFLK PPKKDSEGKK FPCDSVSLDK CSLHLHGYTE RKDIRDTYSS
GSALGMMFGV GNVGDKLLPY EECSTFLTTD GGETWTEVKK GPHQWEYGDH GGVLVLVPEN
AETDSISYST DFGKTWKDYK FCGDKVLVKD IITVPRDSAL RFLLFGEAKN MGSGSFRTYT
IDFRNIFERQ CEFDITGKKR ADFKYSPLGS RTGCLFGHQT EFLRKTDEKC FIGNIPLSEF
SRNVKNCSCT RQDFECDYNF YKASDGTCKL VKGLSSANGA DICKKEPDLI EYYDSSGYRK
IPLSTCKGGL KLDAHLAPHP CPGKEKAFRE KYSINTGAYA LVFVTILLVI FFAAWFVYDR
GIRRNGGFSR FEEIRLGDDG LIENNRTDRV VNIIVRLGLC ISLITKSAFQ RTKAGVARFS
SKLRARFGNR KGPTYSSLLQ GQFSDESDGL HEDANDLSSF TSQDSNFEIE QEDAYRPEQE
HTSQIDQPAT SNIPDALPAR SAIHKPDSTA VRNEDE
