ID   YN95_YEAST              Reviewed;         436 AA.
AC   P53752; D6W1P1;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 141.
DE   RecName: Full=Uncharacterized membrane glycoprotein YNR066C;
GN   OrderedLocusNames=YNR066C; ORFNames=N3543;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169873;
RA   Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K.,
RA   Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K.,
RA   Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M.,
RA   Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F.,
RA   Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F.,
RA   Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C.,
RA   Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A.,
RA   Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H.,
RA   Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L.,
RA   Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R.,
RA   Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D.,
RA   Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A.,
RA   Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C.,
RA   Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F.,
RA   Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G.,
RA   Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M.,
RA   Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
RT   evolutionary implications.";
RL   Nature 387:93-98(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; Z71681; CAA96348.1; -; Genomic_DNA.
DR   EMBL; BK006947; DAA10607.1; -; Genomic_DNA.
DR   PIR; S63398; S63398.
DR   RefSeq; NP_014464.3; NM_001183243.3.
DR   AlphaFoldDB; P53752; -.
DR   BioGRID; 35892; 41.
DR   DIP; DIP-4562N; -.
DR   IntAct; P53752; 1.
DR   MINT; P53752; -.
DR   STRING; 4932.YNR066C; -.
DR   PaxDb; P53752; -.
DR   PRIDE; P53752; -.
DR   EnsemblFungi; YNR066C_mRNA; YNR066C; YNR066C.
DR   GeneID; 855803; -.
DR   KEGG; sce:YNR066C; -.
DR   SGD; S000005349; YNR066C.
DR   VEuPathDB; FungiDB:YNR066C; -.
DR   eggNOG; KOG3511; Eukaryota.
DR   GeneTree; ENSGT00940000180970; -.
DR   HOGENOM; CLU_031415_0_0_1; -.
DR   InParanoid; P53752; -.
DR   OMA; VEWTINP; -.
DR   BioCyc; YEAST:G3O-33370-MON; -.
DR   PRO; PR:P53752; -.
DR   Proteomes; UP000002311; Chromosome XIV.
DR   RNAct; P53752; protein.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0000324; C:fungal-type vacuole; HDA:SGD.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IDA:SGD.
DR   GO; GO:0006895; P:Golgi to endosome transport; IBA:GO_Central.
DR   GO; GO:0006896; P:Golgi to vacuole transport; IBA:GO_Central.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0006623; P:protein targeting to vacuole; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR036278; Sialidase_sf.
DR   InterPro; IPR031778; Sortilin_N.
DR   InterPro; IPR006581; VPS10.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   Pfam; PF15902; Sortilin-Vps10; 1.
DR   SMART; SM00602; VPS10; 1.
DR   SUPFAM; SSF50939; SSF50939; 1.
PE   4: Predicted;
KW   Glycoprotein; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..436
FT                   /note="Uncharacterized membrane glycoprotein YNR066C"
FT                   /id="PRO_0000203484"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REPEAT          57..68
FT                   /note="BNR 1"
FT   REPEAT          101..112
FT                   /note="BNR 2"
FT   REPEAT          229..240
FT                   /note="BNR 3"
FT   REPEAT          394..405
FT                   /note="BNR 4"
FT   CARBOHYD        157
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   436 AA;  49655 MW;  37002190F68E35E8 CRC64;
     MILLQVICTI WTCLFIPLLN AEEFVPKVTE TLSEYSFSLE SFDDSNSLIR LDNQVVWISS
     DSGENWEAVK EIEGHILELI VDPLHGQDRA FVSIHLSPKF YVTDDRGKSW RALTIPVSEN
     CRLGTSCSIA THPTDKKYLI ADCPCFINDN GYIQIQNETY FTNDGESFYN IEPSLKKKED
     DHITSSSCNF VKSSKDSDIE GNDASILCLF SNHGYDSDRH LSAAYTQLAL STDGGKTFKK
     FDEFNDKIIY QYKILKSHII VSTQDDRYNE MSPMDIWISN DASTFQKARL PAQVRHVHMY
     GIYEDSIGRI IIPISTIFTD EKNDQPAPSE ILISDSQGLK FLPVEWTINP HFGYIDIASP
     HFLEGTIIGS FHPSFDYSHN KGKYNKKIAR YETKISVDNG LTWSNLKVVD EENADSFPCD
     ITRPERCSLQ NPFYSI