ID   CBP4_AJECN              Reviewed;         116 AA.
AC   A6R620;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Assembly factor CBP4;
DE   AltName: Full=Cytochrome b mRNA-processing protein 4;
GN   Name=CBP4; ORFNames=HCAG_05078;
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma;
OC   unclassified Histoplasma.
OX   NCBI_TaxID=2059318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Essential for the assembly of ubiquinol-cytochrome c
CC       reductase. It has a direct effect on the correct occurrence of the
CC       Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Single-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CBP4 family. {ECO:0000305}.
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DR   EMBL; CH476659; EDN08579.1; -; Genomic_DNA.
DR   RefSeq; XP_001539611.1; XM_001539561.1.
DR   AlphaFoldDB; A6R620; -.
DR   EnsemblFungi; EDN08579; EDN08579; HCAG_05078.
DR   GeneID; 5445830; -.
DR   KEGG; aje:HCAG_05078; -.
DR   VEuPathDB; FungiDB:HCAG_05078; -.
DR   HOGENOM; CLU_136894_0_0_1; -.
DR   OMA; QWSKSDK; -.
DR   OrthoDB; 1466743at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR012420; Cbp4.
DR   PANTHER; PTHR28202; PTHR28202; 1.
DR   Pfam; PF07960; CBP4; 1.
PE   3: Inferred from homology;
KW   Chaperone; Coiled coil; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..116
FT                   /note="Assembly factor CBP4"
FT                   /id="PRO_0000330116"
FT   TRANSMEM        11..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          76..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          79..116
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   116 AA;  13467 MW;  628BB4DCE73444A6 CRC64;
     MPRIGTTVKM IVAGVLLCIG GPALVQYVRP TEEELFQKFN PELQKRNLET RDQRQKDFDS
     FVTQLKTHAK SDKSIWHAIK ESETTNRREV ETRRKAELEE AERQKAQIRK ELAEGS