ID   YNBD_ECOLI              Reviewed;         430 AA.
AC   P76093; Q2MBC4;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 151.
DE   RecName: Full=Uncharacterized protein YnbD;
GN   Name=ynbD; OrderedLocusNames=b1411, JW1408;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 90-430.
RC   STRAIN=K12;
RA   Kitakawa M., Kasai H., Baba T., Honjo A., Isono K.;
RT   "Nucleotide sequence of the replication terminus region of Escherichia
RT   coli.";
RL   Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- INTERACTION:
CC       P76093; P17169: glmS; NbExp=4; IntAct=EBI-551038, EBI-551022;
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family.
CC       {ECO:0000305}.
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DR   EMBL; U00096; AAC74493.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76432.1; -; Genomic_DNA.
DR   EMBL; D85081; BAA25407.1; -; Genomic_DNA.
DR   PIR; F64892; F64892.
DR   RefSeq; NP_415929.1; NC_000913.3.
DR   RefSeq; WP_001375099.1; NZ_JACEFS010000028.1.
DR   AlphaFoldDB; P76093; -.
DR   SMR; P76093; -.
DR   BioGRID; 4263024; 21.
DR   BioGRID; 850347; 1.
DR   DIP; DIP-12745N; -.
DR   IntAct; P76093; 2.
DR   STRING; 511145.b1411; -.
DR   PaxDb; P76093; -.
DR   PRIDE; P76093; -.
DR   EnsemblBacteria; AAC74493; AAC74493; b1411.
DR   EnsemblBacteria; BAE76432; BAE76432; BAE76432.
DR   GeneID; 945985; -.
DR   KEGG; ecj:JW1408; -.
DR   KEGG; eco:b1411; -.
DR   PATRIC; fig|511145.12.peg.1474; -.
DR   EchoBASE; EB3514; -.
DR   eggNOG; COG0671; Bacteria.
DR   eggNOG; COG2453; Bacteria.
DR   HOGENOM; CLU_031173_0_0_6; -.
DR   InParanoid; P76093; -.
DR   OMA; QHHFIDI; -.
DR   PhylomeDB; P76093; -.
DR   BioCyc; EcoCyc:G6730-MON; -.
DR   PRO; PR:P76093; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.90.190.10; -; 1.
DR   InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR   Pfam; PF00782; DSPc; 1.
DR   SMART; SM00195; DSPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; SSF52799; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Hydrolase; Membrane; Protein phosphatase;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..430
FT                   /note="Uncharacterized protein YnbD"
FT                   /id="PRO_0000094929"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          297..430
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00160"
FT   ACT_SITE        376
FT                   /note="Phosphocysteine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00160"
SQ   SEQUENCE   430 AA;  49563 MW;  7707978DD3F05EB8 CRC64;
     MLQGAGWLLL LAPFFFFTYG SLNQFTAVQD LNSHDIPSQV FGWETAIPFL PWTIVPYWSL
     DLLYGFSLFV CSTTFEQRRL VHRLILATVM ACCGFLLYPL KFSFIRPEVS GVTGWLFSQL
     ELFDLPYNQS PSLHIILCWL LWRHFRQHLA ERWRKVCGGW FLLIAISTLT TWQHHFIDVI
     TGLAVGMLID WMVPVDRRWN YQKPDQRRIK IALPYVVGAG SCIVLMELMM MIQLWWSVWL
     CWPVLSLLII GRGYGGLGAI TTGKDSQGKL PPAVYWLTLP CRIGMWLSMR WFCRRLEPVS
     KMTAGVYLGA FPRHIPAQNA VLDVTFEFPR GRATKDRLYF CVPMLDLVVP EEGELRQAVA
     MLETLREEQG SVLVHCALGL SRSALVVAAW LLCYGHCKTV NEAISYIRAR RPQIVLTDEH
     KAMLRLWENR