CBP4_COCIM
ID CBP4_COCIM Reviewed; 111 AA.
AC Q1DHX9; J3K033;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 1.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=Assembly factor CBP4;
DE AltName: Full=Cytochrome b mRNA-processing protein 4;
GN Name=CBP4; ORFNames=CIMG_10084;
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS;
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=RS;
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- FUNCTION: Essential for the assembly of ubiquinol-cytochrome c
CC reductase. It has a direct effect on the correct occurrence of the
CC Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Single-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CBP4 family. {ECO:0000305}.
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DR EMBL; GG704915; EAS27479.3; -; Genomic_DNA.
DR RefSeq; XP_001239062.1; XM_001239061.2.
DR AlphaFoldDB; Q1DHX9; -.
DR SMR; Q1DHX9; -.
DR EnsemblFungi; EAS27479; EAS27479; CIMG_10084.
DR GeneID; 4557815; -.
DR KEGG; cim:CIMG_10084; -.
DR VEuPathDB; FungiDB:CIMG_10084; -.
DR InParanoid; Q1DHX9; -.
DR OMA; QWSKSDK; -.
DR OrthoDB; 1466743at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR012420; Cbp4.
DR PANTHER; PTHR28202; PTHR28202; 1.
DR Pfam; PF07960; CBP4; 1.
PE 3: Inferred from homology;
KW Chaperone; Coiled coil; Membrane; Mitochondrion;
KW Mitochondrion inner membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..111
FT /note="Assembly factor CBP4"
FT /id="PRO_0000330126"
FT TRANSMEM 10..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 89..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 79..104
FT /evidence="ECO:0000255"
SQ SEQUENCE 111 AA; 12789 MW; 95407EAA8E984314 CRC64;
MGSAWKWTKM ITVGAVVCVG GPMFVNYVRP TEEELFQRFN PELQKRNLAN RDKRQQEFDE
FVTKLKEYSK SDKPIWVVAK EAEELQKKQQ REAALAAKKA AAETPTDKPT Q