ID   YNEE_ECOLI              Reviewed;         304 AA.
AC   P76146; Q2MB96;
DT   21-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=UPF0187 protein YneE;
GN   Name=yneE; OrderedLocusNames=b1520, JW5245;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0187 family. {ECO:0000305}.
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DR   EMBL; U00096; AAC74593.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76460.1; -; Genomic_DNA.
DR   PIR; C64906; C64906.
DR   RefSeq; NP_416037.2; NC_000913.3.
DR   RefSeq; WP_001313828.1; NZ_SSZK01000001.1.
DR   AlphaFoldDB; P76146; -.
DR   SMR; P76146; -.
DR   BioGRID; 4260229; 13.
DR   STRING; 511145.b1520; -.
DR   PaxDb; P76146; -.
DR   PRIDE; P76146; -.
DR   EnsemblBacteria; AAC74593; AAC74593; b1520.
DR   EnsemblBacteria; BAE76460; BAE76460; BAE76460.
DR   GeneID; 946188; -.
DR   KEGG; ecj:JW5245; -.
DR   KEGG; eco:b1520; -.
DR   PATRIC; fig|1411691.4.peg.747; -.
DR   EchoBASE; EB3574; -.
DR   eggNOG; COG3781; Bacteria.
DR   HOGENOM; CLU_029790_4_2_6; -.
DR   InParanoid; P76146; -.
DR   OMA; TDICGAC; -.
DR   PhylomeDB; P76146; -.
DR   BioCyc; EcoCyc:G6807-MON; -.
DR   PRO; PR:P76146; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0005254; F:chloride channel activity; IEA:InterPro.
DR   GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IMP:EcoCyc.
DR   InterPro; IPR021134; Bestrophin/UPF0187.
DR   InterPro; IPR044669; UPF0187.
DR   PANTHER; PTHR33281; PTHR33281; 1.
DR   Pfam; PF01062; Bestrophin; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..304
FT                   /note="UPF0187 protein YneE"
FT                   /id="PRO_0000217663"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   304 AA;  34809 MW;  684DE5BCAA2D0457 CRC64;
     MIVRPQQHWL RRIFVWHGSV LSKISSRLLL NFLFSIAVIF MLPWYTHLGI KFTLAPFSIL
     GVAIAIFLGF RNNAGYARYV EARKLWGQLM IASRSLLREV KTTLPDSASV REFARLQIAF
     AHCLRMTLRK QPQAEVLAHY LKTEDLQRVL ASNSPANRIL LIMGEWLAVQ RRNGQLSDIL
     FISLNDRLND ISAVLAGCER IAYTPIPFAY TLILHRTVYL FCIMLPFALV VDLHYMTPFI
     SVLISYTFIS LDCLAEELED PFGTENNDLP LDAICNAIEI DLLQMNDEAE IPAKILPDRH
     YQLT