ID   YNEE_SALTI              Reviewed;         304 AA.
AC   Q8Z706;
DT   21-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=UPF0187 protein YneE;
GN   Name=yneE; OrderedLocusNames=STY1534, t1448;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0187 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO69090.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=CAD01787.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL513382; CAD01787.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE014613; AAO69090.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_455954.1; NC_003198.1.
DR   RefSeq; WP_001670736.1; NZ_WNTL01000011.1.
DR   AlphaFoldDB; Q8Z706; -.
DR   SMR; Q8Z706; -.
DR   STRING; 220341.16502632; -.
DR   EnsemblBacteria; AAO69090; AAO69090; t1448.
DR   KEGG; stt:t1448; -.
DR   KEGG; sty:STY1534; -.
DR   PATRIC; fig|220341.7.peg.1543; -.
DR   eggNOG; COG3781; Bacteria.
DR   HOGENOM; CLU_029790_4_2_6; -.
DR   OMA; TDICGAC; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005254; F:chloride channel activity; IEA:InterPro.
DR   InterPro; IPR021134; Bestrophin/UPF0187.
DR   InterPro; IPR044669; UPF0187.
DR   PANTHER; PTHR33281; PTHR33281; 1.
DR   Pfam; PF01062; Bestrophin; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..304
FT                   /note="UPF0187 protein YneE"
FT                   /id="PRO_0000217665"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   304 AA;  34942 MW;  6B28C685D147EF48 CRC64;
     MIVRPQQHWI RLIFVWHGSV LSKIFSRLLL NFLLSIAVII MLPWYTMLGI KFTLAPFSIL
     GVAIAIFLGF RNNACYARYV EARHLWGQLM IASRSILREV KTTLPDERGI EDFVRLQIAF
     AHCLRMTLRR QPQTQVLGNY LDQEALQKVV ASHSPANRIL LLMGEWLAIR RRSGKLSDIL
     FHSLNNRLND MSSVLAGCER IANTPVPFAY TLILHRTVYL FCIMLPFALV VDLHYMTPFI
     SVLISYTFIA LDALAEELED PFGTENNDLP LDAICNAIEI DLLQMNDERD IPAKRIPDKR
     YQLT