YNEE_SALTY
ID YNEE_SALTY Reviewed; 304 AA.
AC Q8ZPI0;
DT 21-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 2.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=UPF0187 protein YneE;
GN Name=yneE; OrderedLocusNames=STM1527;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0187 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL20446.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE006468; AAL20446.1; ALT_INIT; Genomic_DNA.
DR RefSeq; NP_460487.1; NC_003197.2.
DR AlphaFoldDB; Q8ZPI0; -.
DR SMR; Q8ZPI0; -.
DR STRING; 99287.STM1527; -.
DR PaxDb; Q8ZPI0; -.
DR EnsemblBacteria; AAL20446; AAL20446; STM1527.
DR GeneID; 1253045; -.
DR KEGG; stm:STM1527; -.
DR PATRIC; fig|99287.12.peg.1615; -.
DR HOGENOM; CLU_029790_4_2_6; -.
DR PhylomeDB; Q8ZPI0; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005254; F:chloride channel activity; IEA:InterPro.
DR InterPro; IPR021134; Bestrophin/UPF0187.
DR InterPro; IPR044669; UPF0187.
DR PANTHER; PTHR33281; PTHR33281; 1.
DR Pfam; PF01062; Bestrophin; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..304
FT /note="UPF0187 protein YneE"
FT /id="PRO_0000217666"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 304 AA; 34942 MW; 6B28C685D147EF48 CRC64;
MIVRPQQHWI RLIFVWHGSV LSKIFSRLLL NFLLSIAVII MLPWYTMLGI KFTLAPFSIL
GVAIAIFLGF RNNACYARYV EARHLWGQLM IASRSILREV KTTLPDERGI EDFVRLQIAF
AHCLRMTLRR QPQTQVLGNY LDQEALQKVV ASHSPANRIL LLMGEWLAIR RRSGKLSDIL
FHSLNNRLND MSSVLAGCER IANTPVPFAY TLILHRTVYL FCIMLPFALV VDLHYMTPFI
SVLISYTFIA LDALAEELED PFGTENNDLP LDAICNAIEI DLLQMNDERD IPAKRIPDKR
YQLT