ID   YNF8_LACTC              Reviewed;         298 AA.
AC   C5DMK0;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Vacuolar membrane protein KLTH0G09570g;
GN   OrderedLocusNames=KLTH0G09570g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PRM5 family. {ECO:0000305}.
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DR   EMBL; CU928171; CAR25011.1; -; Genomic_DNA.
DR   RefSeq; XP_002555448.1; XM_002555402.1.
DR   AlphaFoldDB; C5DMK0; -.
DR   STRING; 559295.C5DMK0; -.
DR   EnsemblFungi; CAR25011; CAR25011; KLTH0G09570g.
DR   GeneID; 8293726; -.
DR   KEGG; lth:KLTH0G09570g; -.
DR   eggNOG; ENOG502S625; Eukaryota.
DR   HOGENOM; CLU_061224_0_0_1; -.
DR   InParanoid; C5DMK0; -.
DR   OMA; KINSMEG; -.
DR   OrthoDB; 1486670at2759; -.
DR   Proteomes; UP000002036; Chromosome G.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix; Vacuole.
FT   CHAIN           1..298
FT                   /note="Vacuolar membrane protein KLTH0G09570g"
FT                   /id="PRO_0000409318"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          123..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          226..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        258..272
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..298
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   298 AA;  32462 MW;  D152612BCBCCF60F CRC64;
     MVHQTDFISS TAILKTQKAS TSLVHATMFE RAMPSLTNAG KASSTKTYTT PTITPPSIKG
     NPHIWSSDKP SGTLFIAVGS VVGFIFLIIA LAYIVSAYIS RRQTEKLRFE TIDQEFQSHV
     GGKSYSKLGN SDDPEKSGFL SKAVHTPQSR SVARLLDRPD FQQPSPALSN QDSSTSLAQE
     FYSSIRDQTA AQNRKSLFIS PTVEIVNQQR KSAVLQNMNN SVSSLVSDSG AELNKPEKAA
     PSTRKAMYKA RNKSSMGSAV GIAKSRSTSP VKSGLRDKPL DRAKTPSVYL DKMFEDES