ID   YNF8_VANPO              Reviewed;         343 AA.
AC   A7TLX5;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=Vacuolar membrane protein Kpol_1003p17;
GN   ORFNames=Kpol_1003p17;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Single-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PRM5 family. {ECO:0000305}.
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DR   EMBL; DS480418; EDO16712.1; -; Genomic_DNA.
DR   RefSeq; XP_001644570.1; XM_001644520.1.
DR   AlphaFoldDB; A7TLX5; -.
DR   SMR; A7TLX5; -.
DR   STRING; 436907.A7TLX5; -.
DR   EnsemblFungi; EDO16712; EDO16712; Kpol_1003p17.
DR   GeneID; 5544879; -.
DR   KEGG; vpo:Kpol_1003p17; -.
DR   eggNOG; ENOG502S625; Eukaryota.
DR   HOGENOM; CLU_061224_0_0_1; -.
DR   InParanoid; A7TLX5; -.
DR   OMA; KINSMEG; -.
DR   OrthoDB; 1486670at2759; -.
DR   PhylomeDB; A7TLX5; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix; Vacuole.
FT   CHAIN           1..343
FT                   /note="Vacuolar membrane protein Kpol_1003p17"
FT                   /id="PRO_0000409319"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          45..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          235..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        315..329
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   343 AA;  38046 MW;  BF9C39BAD7769F12 CRC64;
     MNGSLNIRGL PKLTTSTSIS VSSTSASSTL STTTLSSNSI ISSITTDTSG TSTSSRDVSS
     GQSTLNSIST TSSIIVPSIT PPSAAKNPNV WHSEDSDGTV FIAVGSIIGG IFGGVLIWWM
     ITSYLSHVKT KKAYHSDMEE QYMSHLNGGS PHKVGSYHDD KSKIENPFSS FYMDDLESSN
     KKKYSRVSLV SDNPFDEDLD YALDTTEQVR YNPIQDETNH YANKKDTLFI SPTKEVLQQQ
     RQRRESKLFD NPSELPSTPP SNFKTLMLKP ERSASPERKS RSPIRQHRKN NSSVQLTPLK
     LDSGEDDFKK TPTKKKNVNN SNNNNKHKKT PSMYLDDMLE NDN