CBP4_NEUCR
ID CBP4_NEUCR Reviewed; 125 AA.
AC Q7SDU5;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Assembly factor cbp-4;
DE AltName: Full=Cytochrome b mRNA-processing protein 4;
GN Name=cbp-4; ORFNames=5C2.060, NCU03147;
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX PubMed=12655011; DOI=10.1093/nar/gkg293;
RA Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D.,
RA Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
RT "What's in the genome of a filamentous fungus? Analysis of the Neurospora
RT genome sequence.";
RL Nucleic Acids Res. 31:1944-1954(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- FUNCTION: Essential for the assembly of ubiquinol-cytochrome c
CC reductase. It has a direct effect on the correct occurrence of the
CC Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Single-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CBP4 family. {ECO:0000305}.
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DR EMBL; BX842637; CAE76549.1; -; Genomic_DNA.
DR EMBL; CM002236; EAA34960.1; -; Genomic_DNA.
DR RefSeq; XP_964196.1; XM_959103.2.
DR AlphaFoldDB; Q7SDU5; -.
DR SMR; Q7SDU5; -.
DR STRING; 5141.EFNCRP00000002965; -.
DR EnsemblFungi; EAA34960; EAA34960; NCU03147.
DR GeneID; 3880345; -.
DR KEGG; ncr:NCU03147; -.
DR VEuPathDB; FungiDB:NCU03147; -.
DR HOGENOM; CLU_136894_1_1_1; -.
DR InParanoid; Q7SDU5; -.
DR OMA; QWSKSDK; -.
DR Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR GO; GO:0032592; C:integral component of mitochondrial membrane; IBA:GO_Central.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IBA:GO_Central.
DR InterPro; IPR012420; Cbp4.
DR PANTHER; PTHR28202; PTHR28202; 1.
DR Pfam; PF07960; CBP4; 1.
PE 3: Inferred from homology;
KW Chaperone; Coiled coil; Membrane; Mitochondrion;
KW Mitochondrion inner membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..125
FT /note="Assembly factor cbp-4"
FT /id="PRO_0000330133"
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT COILED 98..118
FT /evidence="ECO:0000255"
SQ SEQUENCE 125 AA; 14650 MW; ADFA56AC5B977BB5 CRC64;
MAAKKPVNWW LWTKMLLGGA AICVGGPAFT YWLTPTDEEL FQKYNPELQK RSLERRFERQ
QEFDDFVTKL KEYSKSDKPI WTVQAEAEEK ERQQRASVQK SLALADEVKA RKEAMRREAG
LPLEK