CBP4_PICGU
ID CBP4_PICGU Reviewed; 143 AA.
AC A5DM93;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 2.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=Assembly factor CBP4;
DE AltName: Full=Cytochrome b mRNA-processing protein 4;
GN Name=CBP4; ORFNames=PGUG_04394;
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Essential for the assembly of ubiquinol-cytochrome c
CC reductase. It has a direct effect on the correct occurrence of the
CC Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Single-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CBP4 family. {ECO:0000305}.
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DR EMBL; CH408159; EDK40296.2; -; Genomic_DNA.
DR RefSeq; XP_001483665.1; XM_001483615.1.
DR AlphaFoldDB; A5DM93; -.
DR STRING; 294746.A5DM93; -.
DR EnsemblFungi; EDK40296; EDK40296; PGUG_04394.
DR GeneID; 5125648; -.
DR KEGG; pgu:PGUG_04394; -.
DR VEuPathDB; FungiDB:PGUG_04394; -.
DR eggNOG; ENOG502S2G8; Eukaryota.
DR HOGENOM; CLU_147520_0_0_1; -.
DR InParanoid; A5DM93; -.
DR OMA; YRWARVG; -.
DR OrthoDB; 1466743at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR012420; Cbp4.
DR PANTHER; PTHR28202; PTHR28202; 1.
DR Pfam; PF07960; CBP4; 1.
PE 3: Inferred from homology;
KW Chaperone; Coiled coil; Membrane; Mitochondrion;
KW Mitochondrion inner membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..143
FT /note="Assembly factor CBP4"
FT /id="PRO_0000330135"
FT TRANSMEM 13..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 110..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 103..139
FT /evidence="ECO:0000255"
FT COMPBIAS 112..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 143 AA; 16814 MW; 79BBF32D5DA77EFB CRC64;
MSTRPLWYRW ARVGFYGGAI IATGVVLFKY TTPTDEQLIA SFSPEVRAEY EKSRELRQKE
QQALMEIVKK TSASNDPIWK TGSIKSPFEK DGRYVDPKLV DPQALLRESA AEQQRIETEE
ANRKMEETER LLNEKRKKWW SWK
