YNJ5_YEAST
ID YNJ5_YEAST Reviewed; 642 AA.
AC P53932; D6W185;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Uncharacterized transporter YNL095C;
GN OrderedLocusNames=YNL095C; ORFNames=N2215;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=8771715;
RX DOI=10.1002/(sici)1097-0061(199605)12:6<599::aid-yea938>3.0.co;2-9;
RA Garcia-Cantalejo J.M., Boskovic J., Jimenez A.;
RT "Sequence analysis of a 14.2 kb fragment of Saccharomyces cerevisiae
RT chromosome XIV that includes the ypt53, tRNALeu and gsr m2 genes and four
RT new open reading frames.";
RL Yeast 12:599-608(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169873;
RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K.,
RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K.,
RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M.,
RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F.,
RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F.,
RA Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C.,
RA Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A.,
RA Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H.,
RA Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L.,
RA Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R.,
RA Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D.,
RA Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A.,
RA Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C.,
RA Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F.,
RA Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G.,
RA Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M.,
RA Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
RT evolutionary implications.";
RL Nature 387:93-98(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 208353 / W303-1A;
RX PubMed=16847258; DOI=10.1073/pnas.0604075103;
RA Kim H., Melen K., Oesterberg M., von Heijne G.;
RT "A global topology map of the Saccharomyces cerevisiae membrane proteome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006).
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69) family.
CC {ECO:0000305}.
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DR EMBL; X85811; CAA59822.1; -; Genomic_DNA.
DR EMBL; Z71371; CAA95971.1; -; Genomic_DNA.
DR EMBL; BK006947; DAA10451.1; -; Genomic_DNA.
DR PIR; S52730; S52730.
DR RefSeq; NP_014304.1; NM_001182933.1.
DR AlphaFoldDB; P53932; -.
DR BioGRID; 35729; 52.
DR DIP; DIP-4349N; -.
DR STRING; 4932.YNL095C; -.
DR iPTMnet; P53932; -.
DR MaxQB; P53932; -.
DR PaxDb; P53932; -.
DR PRIDE; P53932; -.
DR EnsemblFungi; YNL095C_mRNA; YNL095C; YNL095C.
DR GeneID; 855629; -.
DR KEGG; sce:YNL095C; -.
DR SGD; S000005039; YNL095C.
DR VEuPathDB; FungiDB:YNL095C; -.
DR eggNOG; ENOG502QU6H; Eukaryota.
DR GeneTree; ENSGT00940000176363; -.
DR HOGENOM; CLU_021924_0_0_1; -.
DR InParanoid; P53932; -.
DR BioCyc; YEAST:G3O-33123-MON; -.
DR PRO; PR:P53932; -.
DR Proteomes; UP000002311; Chromosome XIV.
DR RNAct; P53932; protein.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR040254; Ecm3-like.
DR InterPro; IPR004776; Mem_trans.
DR PANTHER; PTHR31274; PTHR31274; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..642
FT /note="Uncharacterized transporter YNL095C"
FT /id="PRO_0000123807"
FT TOPO_DOM 1..15
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 37..42
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 64..73
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 95..104
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 126..142
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 164..460
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 461..481
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 482..499
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 500..520
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 521..538
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 539..559
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 560..574
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 575..595
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 596..614
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 615..635
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 636..642
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 183..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 642 AA; 71196 MW; E4E3253D929FF4E2 CRC64;
MVHITLGQAI WVSVKPIIKI YLIIGVGFLM AKMGILTVEA TRIISDIVLT VLLPSLSFNK
IVANIEDKDI KSVGIICLSA LLIFGSGFFF AYVVRLFLPV PKQWYGGILA GGMFPNISDL
PIAYLQSMDQ GLVFSEEEGN KGVANVIIFL TMFLICIFNL GGFRLIESDF EYNDDESAVR
VSETTKTQPA VSANTTNTDT SERFFSNEQQ LFNNKYTARD SLTEAIGTKG ENADVPPISR
RSTNSIAPLS LPDTSSNSKI TKPVQVKARN TIACTQSEES QATRGSNPLD SQSSASTIHS
YNTSESYESS IDTMRARRTA SQPRAYNTTT LLEENCLDEK CPKNMSMAAL EPIRSIDMRA
LPSQNIHHLI REYSNVDQYG HQRRNSSLRG ADMNDVHSIS SNSTLQTIKT ANLTRILTSD
ATVSKKDIET SGESLPQWMR KFSLTPLLVF FLKNCLRPCS MAVIIALTVA FIPWVKALFV
TTANTPHISQ APDNAPPLSF FMDFTGYVGA ACVPFGLILL GATLGRLKIG NLYPGFWKAA
VTLVILRQCV MPIFGVLWCD RLVKAGWVNW QDDRMLLFVI AISWNLPTMT TLIYFTASFT
PPETTAPIQM ECVSFFLMLQ YPLMVVSLPF LVSYFLKVQM NL
