YNK8_YEAST
ID YNK8_YEAST Reviewed; 270 AA.
AC P53929; D6W172;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Uncharacterized protein YNL108C;
GN OrderedLocusNames=YNL108C; ORFNames=N1962;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9090055;
RX DOI=10.1002/(sici)1097-0061(19970315)13:3<261::aid-yea64>3.0.co;2-l;
RA de Antoni A., D'Angelo M., Dal Pero F., Sartorello F., Pandolfo D.,
RA Pallavicini A., Lanfranchi G., Valle G.;
RT "The DNA sequence of cosmid 14-13b from chromosome XIV of Saccharomyces
RT cerevisiae reveals an unusually high number of overlapping open reading
RT frames.";
RL Yeast 13:261-266(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169873;
RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K.,
RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K.,
RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M.,
RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F.,
RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F.,
RA Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C.,
RA Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A.,
RA Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H.,
RA Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L.,
RA Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R.,
RA Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D.,
RA Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A.,
RA Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C.,
RA Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F.,
RA Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G.,
RA Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M.,
RA Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
RT evolutionary implications.";
RL Nature 387:93-98(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-terminal
RT acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- MISCELLANEOUS: Present with 1950 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: To yeast YOR110w. {ECO:0000305}.
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DR EMBL; Z69382; CAA93399.1; -; Genomic_DNA.
DR EMBL; Z71385; CAA95988.1; -; Genomic_DNA.
DR EMBL; BK006947; DAA10438.1; -; Genomic_DNA.
DR PIR; S63049; S63049.
DR RefSeq; NP_014291.1; NM_001182946.1.
DR PDB; 2YN2; X-ray; 2.05 A; A=1-270.
DR PDBsum; 2YN2; -.
DR AlphaFoldDB; P53929; -.
DR SMR; P53929; -.
DR BioGRID; 35716; 70.
DR IntAct; P53929; 3.
DR STRING; 4932.YNL108C; -.
DR MaxQB; P53929; -.
DR PaxDb; P53929; -.
DR PRIDE; P53929; -.
DR EnsemblFungi; YNL108C_mRNA; YNL108C; YNL108C.
DR GeneID; 855615; -.
DR KEGG; sce:YNL108C; -.
DR SGD; S000005052; YNL108C.
DR VEuPathDB; FungiDB:YNL108C; -.
DR eggNOG; ENOG502RYP8; Eukaryota.
DR GeneTree; ENSGT00940000167071; -.
DR HOGENOM; CLU_042838_0_0_1; -.
DR InParanoid; P53929; -.
DR OMA; GEEMHWD; -.
DR BioCyc; YEAST:G3O-33133-MON; -.
DR PRO; PR:P53929; -.
DR Proteomes; UP000002311; Chromosome XIV.
DR RNAct; P53929; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR GO; GO:0016791; F:phosphatase activity; IDA:SGD.
DR GO; GO:0016311; P:dephosphorylation; IDA:SGD.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.1240; -; 1.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR014623; Tfc7/tau55.
DR Pfam; PF00300; His_Phos_1; 1.
DR PIRSF; PIRSF036802; Tau55_TFC7; 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF53254; SSF53254; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..270
FT /note="Uncharacterized protein YNL108C"
FT /id="PRO_0000203436"
FT STRAND 5..10
FT /evidence="ECO:0007829|PDB:2YN2"
FT HELIX 15..17
FT /evidence="ECO:0007829|PDB:2YN2"
FT STRAND 18..20
FT /evidence="ECO:0007829|PDB:2YN2"
FT HELIX 38..52
FT /evidence="ECO:0007829|PDB:2YN2"
FT STRAND 61..63
FT /evidence="ECO:0007829|PDB:2YN2"
FT HELIX 67..80
FT /evidence="ECO:0007829|PDB:2YN2"
FT STRAND 84..86
FT /evidence="ECO:0007829|PDB:2YN2"
FT HELIX 88..90
FT /evidence="ECO:0007829|PDB:2YN2"
FT HELIX 107..113
FT /evidence="ECO:0007829|PDB:2YN2"
FT TURN 115..117
FT /evidence="ECO:0007829|PDB:2YN2"
FT HELIX 135..156
FT /evidence="ECO:0007829|PDB:2YN2"
FT STRAND 162..167
FT /evidence="ECO:0007829|PDB:2YN2"
FT HELIX 169..179
FT /evidence="ECO:0007829|PDB:2YN2"
FT STRAND 185..187
FT /evidence="ECO:0007829|PDB:2YN2"
FT STRAND 189..192
FT /evidence="ECO:0007829|PDB:2YN2"
FT STRAND 203..207
FT /evidence="ECO:0007829|PDB:2YN2"
FT HELIX 218..220
FT /evidence="ECO:0007829|PDB:2YN2"
FT STRAND 224..230
FT /evidence="ECO:0007829|PDB:2YN2"
FT STRAND 246..248
FT /evidence="ECO:0007829|PDB:2YN2"
FT HELIX 253..262
FT /evidence="ECO:0007829|PDB:2YN2"
SQ SEQUENCE 270 AA; 30748 MW; 960CBE9044C3202E CRC64;
MAIENIYIAR HGYRSNWLPK GPYPPPPTGI DNDVPLSEHG VEQAHELANY ISKLDVKPEM
IFSSPFYRCL ETSKPTVEAL KIPLYVDRGV GEWYKPDRPI IPEPATHEVM SKFFPSMISP
DWEPSIIPSN KGETEEDIFE RCHKFWPVFI DRVERKFPNV KTIMIVTHAA TKSALGMNLL
KFSSAKEPID NKGTFIRNGS CAIDKFELVK GENESIPFEE REWKLTMNGN TSFLTNGEEM
NWTFMNAFEA GSDADIKARR AAESGKLKME
