ID   YNO6_YEAST              Reviewed;         100 AA.
AC   P53906; D6W137;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 2.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Uncharacterized protein YNL146W;
GN   OrderedLocusNames=YNL146W; ORFNames=N1203, N1785;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8619318; DOI=10.1002/yea.320111210;
RA   Mallet L., Bussereau F., Jacquet M.;
RT   "A 43.5 kb segment of yeast chromosome XIV, which contains MFA2, MEP2,
RT   CAP/SRV2, NAM9, FKB1/FPR1/RBP1, MOM22 and CPT1, predicts an adenosine
RT   deaminase gene and 14 new open reading frames.";
RL   Yeast 11:1195-1209(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 96604 / S288c / FY1679;
RX   PubMed=8686380;
RX   DOI=10.1002/(sici)1097-0061(199602)12:2<169::aid-yea894>3.0.co;2-b;
RA   Nasr F., Becam A.-M., Herbert C.J.;
RT   "The sequence of 36.8 kb from the left arm of chromosome XIV reveals 24
RT   complete open reading frames: 18 correspond to new genes, one of which
RT   encodes a protein similar to the human myotonic dystrophy kinase.";
RL   Yeast 12:169-175(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169873;
RA   Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K.,
RA   Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K.,
RA   Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M.,
RA   Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F.,
RA   Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F.,
RA   Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C.,
RA   Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A.,
RA   Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H.,
RA   Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L.,
RA   Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R.,
RA   Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D.,
RA   Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A.,
RA   Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C.,
RA   Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F.,
RA   Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G.,
RA   Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M.,
RA   Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
RT   evolutionary implications.";
RL   Nature 387:93-98(1997).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [5]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=14562095; DOI=10.1038/nature02026;
RA   Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA   Weissman J.S., O'Shea E.K.;
RT   "Global analysis of protein localization in budding yeast.";
RL   Nature 425:686-691(2003).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
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DR   EMBL; Z46843; CAA86880.1; -; Genomic_DNA.
DR   EMBL; X92517; CAA63293.1; -; Genomic_DNA.
DR   EMBL; Z71422; CAA96029.1; -; Genomic_DNA.
DR   EMBL; BK006947; DAA10403.1; -; Genomic_DNA.
DR   PIR; S60981; S60981.
DR   RefSeq; NP_014253.3; NM_001182984.3.
DR   AlphaFoldDB; P53906; -.
DR   SMR; P53906; -.
DR   BioGRID; 35682; 74.
DR   DIP; DIP-8009N; -.
DR   IntAct; P53906; 2.
DR   MINT; P53906; -.
DR   STRING; 4932.YNL146W; -.
DR   PaxDb; P53906; -.
DR   PRIDE; P53906; -.
DR   EnsemblFungi; YNL146W_mRNA; YNL146W; YNL146W.
DR   GeneID; 855576; -.
DR   KEGG; sce:YNL146W; -.
DR   SGD; S000005090; YNL146W.
DR   VEuPathDB; FungiDB:YNL146W; -.
DR   HOGENOM; CLU_175726_0_0_1; -.
DR   OMA; IFDRTLM; -.
DR   BioCyc; YEAST:G3O-33164-MON; -.
DR   PRO; PR:P53906; -.
DR   Proteomes; UP000002311; Chromosome XIV.
DR   RNAct; P53906; protein.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..100
FT                   /note="Uncharacterized protein YNL146W"
FT                   /id="PRO_0000203422"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        15
FT                   /note="K -> I (in Ref. 1; CAA86880)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        21
FT                   /note="T -> R (in Ref. 1; CAA86880)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   100 AA;  11887 MW;  FD6E21B72C1C2368 CRC64;
     MSNTKHTTSH HMELKRIIIL TLLFILIMLI FRNSVSFKMT FQELLPRFYK KNSNSVSNNN
     RPSSIFSENL VDFDDVNMVD KTRLFIFLFF SFIITIPFMV