YNS5_SCHPO
ID YNS5_SCHPO Reviewed; 586 AA.
AC O60136;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Uncharacterized WD repeat-containing protein C18H10.05;
GN ORFNames=SPBC18H10.05;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}. Note=Localizes at the cell tip and the
CC barrier septum.
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DR EMBL; CU329671; CAA18402.1; -; Genomic_DNA.
DR PIR; T39769; T39769.
DR RefSeq; NP_595729.1; NM_001021627.2.
DR AlphaFoldDB; O60136; -.
DR SMR; O60136; -.
DR BioGRID; 277350; 29.
DR STRING; 4896.SPBC18H10.05.1; -.
DR iPTMnet; O60136; -.
DR PaxDb; O60136; -.
DR PRIDE; O60136; -.
DR EnsemblFungi; SPBC18H10.05.1; SPBC18H10.05.1:pep; SPBC18H10.05.
DR GeneID; 2540832; -.
DR KEGG; spo:SPBC18H10.05; -.
DR PomBase; SPBC18H10.05; -.
DR VEuPathDB; FungiDB:SPBC18H10.05; -.
DR eggNOG; KOG0283; Eukaryota.
DR HOGENOM; CLU_465518_0_0_1; -.
DR InParanoid; O60136; -.
DR OMA; ISWSKND; -.
DR PhylomeDB; O60136; -.
DR PRO; PR:O60136; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0051286; C:cell tip; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR040324; WDR44/Dgr2.
DR PANTHER; PTHR14221; PTHR14221; 1.
DR Pfam; PF00400; WD40; 2.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Cytoplasm; Nucleus; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..586
FT /note="Uncharacterized WD repeat-containing protein
FT C18H10.05"
FT /id="PRO_0000316568"
FT REPEAT 184..223
FT /note="WD 1"
FT REPEAT 253..291
FT /note="WD 2"
FT REPEAT 293..333
FT /note="WD 3"
FT REPEAT 335..374
FT /note="WD 4"
FT REPEAT 387..430
FT /note="WD 5"
FT REPEAT 432..474
FT /note="WD 6"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 66078 MW; 993D5A9361AD161B CRC64;
MRVLVAETGR EDNVSVHSRE VSVNGSDSGT GNDAYKLETD DEHPPATPVR GLSTRSQKRP
FRPLTIQQDE DVENDTGMNT EYNDDNSSLV NTPRDSTTYA ETNSPNTEKL AGRDDDRSLL
NLIDRGEIDS KRQRHYVPVH CKRMPKKEIT LNQKLYVSQV IGPADAPKSK TIFGKRIMQW
EPSQFKESVW ASEISKSGKY LATAGKDAII RVWKVIETPE RRETLLKEGP QSCGRFFTPS
SIFEPEPVLE CVGHNAEVLS ISWSKNDFLL TSSADRTVRL WHPKSTKSLA VFRHNEIVTC
VAFHPIDDRY FVSGSLDCKI QLWSILRHKI LHWTELEYVV STICFYPDGE SIVVGMFYGL
CAIYETKNLQ YVSSWLIHHS PSRNKKCRVT GLQCASIIPN DSKSDNVVLV STNDNAIRLY
NTVTHALVLK LSDAHRVNGR VLSRLSEDNS YIISGSDTNE VVLWHIPNKV LINASRKRSV
ILHLPTETFK VCSERLTSTI IAPARTAVEA KESEHDRSLI AEGYNLVKPH SHRSYGTPPV
HPIDIIIATN MAGMTIVLCV DYDLGNSHHG FRNSKFGHFV KRLLRT
