ID   YO08A_YEAST             Reviewed;          74 AA.
AC   Q3E7B9; D6W275;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Uncharacterized protein YOR008C-A;
DE   Flags: Precursor;
GN   OrderedLocusNames=YOR008C-A;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169874;
RA   Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA   Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA   Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA   Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA   Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA   Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA   Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA   Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA   Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA   Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA   Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA   Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA   Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA   Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA   Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA   Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA   Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL   Nature 387:98-102(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   POSSIBLE FUNCTION.
RX   PubMed=15161972; DOI=10.1073/pnas.0401263101;
RA   Askree S.H., Yehuda T., Smolikov S., Gurevich R., Hawk J., Coker C.,
RA   Krauskopf A., Kupiec M., McEachern M.J.;
RT   "A genome-wide screen for Saccharomyces cerevisiae deletion mutants that
RT   affect telomere length.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:8658-8663(2004).
CC   -!- FUNCTION: May be involved in the regulation of telomere length.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
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DR   EMBL; Z74917; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BK006948; DAA10791.1; -; Genomic_DNA.
DR   RefSeq; NP_014651.1; NM_001184305.1.
DR   AlphaFoldDB; Q3E7B9; -.
DR   BioGRID; 34413; 112.
DR   PaxDb; Q3E7B9; -.
DR   EnsemblFungi; YOR008C-A_mRNA; YOR008C-A; YOR008C-A.
DR   GeneID; 854171; -.
DR   KEGG; sce:YOR008C-A; -.
DR   SGD; S000006431; YOR008C-A.
DR   VEuPathDB; FungiDB:YOR008C-A; -.
DR   HOGENOM; CLU_2689705_0_0_1; -.
DR   BioCyc; YEAST:G3O-33854-MON; -.
DR   PRO; PR:Q3E7B9; -.
DR   Proteomes; UP000002311; Chromosome XV.
DR   RNAct; Q3E7B9; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..74
FT                   /note="Uncharacterized protein YOR008C-A"
FT                   /id="PRO_0000235935"
FT   TOPO_DOM        19..21
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        22..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        45..74
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   74 AA;  8604 MW;  6ABFFE2313B6F481 CRC64;
     MWRSYLVFLF FMTPRIQTYC PVPVLRSMAV LNIISPLIIF VSPIKKQDSL HSSACYANLT
     LVEKLQLWHS MSND