YO163_YEAST
ID YO163_YEAST Reviewed; 169 AA.
AC P0CF20; D6W1Q7; Q08330; Q08337;
DT 20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT 20-APR-2010, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Putative uncharacterized transporter YOL163W;
GN OrderedLocusNames=YOL163W; ORFNames=O0230;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Allantoate
CC permease family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. This is a truncated
CC version of an allantoate permease subfamily member protein. Strain
CC S288c has a stop codon in position 170, which disrupts the gene coding
CC for this protein and produces two ORFs YOL163W and YOL162W.
CC {ECO:0000305}.
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DR EMBL; Z74905; CAA99185.1; -; Genomic_DNA.
DR EMBL; AY692667; AAT92686.1; -; Genomic_DNA.
DR EMBL; BK006948; DAA10623.1; -; Genomic_DNA.
DR PIR; S66862; S66862.
DR RefSeq; NP_014479.1; NM_001183416.1.
DR AlphaFoldDB; P0CF20; -.
DR BioGRID; 34255; 22.
DR STRING; 4932.YOL163W; -.
DR PaxDb; P0CF20; -.
DR PRIDE; P0CF20; -.
DR EnsemblFungi; YOL163W_mRNA; YOL163W; YOL163W.
DR GeneID; 854001; -.
DR KEGG; sce:YOL163W; -.
DR SGD; S000005523; YOL163W.
DR VEuPathDB; FungiDB:YOL163W; -.
DR eggNOG; KOG2533; Eukaryota.
DR GeneTree; ENSGT00940000176452; -.
DR HOGENOM; CLU_112733_0_0_1; -.
DR InParanoid; P0CF20; -.
DR OMA; HAGLEGW; -.
DR BioCyc; YEAST:G3O-33550-MON; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; P0CF20; protein.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031224; C:intrinsic component of membrane; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; ISS:SGD.
DR GO; GO:0022857; F:transmembrane transporter activity; ISM:SGD.
DR GO; GO:0055085; P:transmembrane transport; ISM:SGD.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 5: Uncertain;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..169
FT /note="Putative uncharacterized transporter YOL163W"
FT /id="PRO_0000393392"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 169 AA; 19462 MW; BDBF0AC09E15B1DA CRC64;
MIAWSLVATL QCKMTGKSSF YTCRALMGLF EGGFVADLVL WMSYFYSSSE LSIRLSFFWV
TLSLTQIITS IVAFGVFHMR GIGGMAGWQW LFLIERIFTL VIGISAYFLM VPSVVQTKKP
WSKKGWFTER EEKIIVNKIL RDDPTKGDMN NRQGMSLKML WQGITDYYI