YO296_YEAST
ID YO296_YEAST Reviewed; 1289 AA.
AC Q08748; D6W2Z5;
DT 11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Uncharacterized protein YOR296W;
GN OrderedLocusNames=YOR296W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9153758;
RX DOI=10.1002/(sici)1097-0061(199704)13:5<479::aid-yea104>3.0.co;2-g;
RA Poirey R., Cziepluch C., Tobiasch E., Pujol A., Kordes E., Jauniaux J.-C.;
RT "Sequence and analysis of a 36.2 kb fragment from the right arm of yeast
RT chromosome XV reveals 19 open reading frames including SNF2 (5' end), CPA1,
RT SLY41, a putative transport ATPase, a putative ribosomal protein and an
RT SNF2 homologue.";
RL Yeast 13:479-482(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 300 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z75204; CAA99524.1; -; Genomic_DNA.
DR EMBL; BK006948; DAA11061.1; -; Genomic_DNA.
DR PIR; S67200; S67200.
DR RefSeq; NP_014939.1; NM_001183715.1.
DR AlphaFoldDB; Q08748; -.
DR SMR; Q08748; -.
DR BioGRID; 34684; 90.
DR IntAct; Q08748; 2.
DR MINT; Q08748; -.
DR iPTMnet; Q08748; -.
DR MaxQB; Q08748; -.
DR PaxDb; Q08748; -.
DR PRIDE; Q08748; -.
DR EnsemblFungi; YOR296W_mRNA; YOR296W; YOR296W.
DR GeneID; 854471; -.
DR KEGG; sce:YOR296W; -.
DR SGD; S000005822; YOR296W.
DR VEuPathDB; FungiDB:YOR296W; -.
DR eggNOG; ENOG502QQWJ; Eukaryota.
DR GeneTree; ENSGT00730000110939; -.
DR HOGENOM; CLU_003023_1_0_1; -.
DR InParanoid; Q08748; -.
DR OMA; VMTRLWK; -.
DR BioCyc; YEAST:G3O-33781-MON; -.
DR PRO; PR:Q08748; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; Q08748; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR Gene3D; 2.60.40.150; -; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR014770; Munc13_1.
DR InterPro; IPR014772; Munc13_dom-2.
DR Pfam; PF00168; C2; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; SSF49562; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS51258; MHD1; 1.
DR PROSITE; PS51259; MHD2; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..1289
FT /note="Uncharacterized protein YOR296W"
FT /id="PRO_0000245284"
FT DOMAIN 615..733
FT /note="MHD1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00587"
FT DOMAIN 834..966
FT /note="C2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00041"
FT DOMAIN 1044..1184
FT /note="MHD2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00588"
FT REGION 745..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..771
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1289 AA; 147426 MW; 7A14FF984D38480B CRC64;
MNRTVSTLSS TVSDVSVEIP SICNVINTEL PTSDVYLYTL KLILLDYINE PRFKEAALLS
NRTGTSRVLS DKTNHQQTQH GKKLVVDKQD DMSERDIVQA TLRILKGKLA QISGNKNLAP
NEMHWKSIVK MYYSMLDSSS ADTFSKMGQM EEVVGYFTNI ASNELKKMTI KNSRDELFSE
VAYFIDLVID VLPDSCANII KRLLDYKINL KKGETTVKKK RAASPATVPQ YRSISGSTIS
NKQPSFKVQD ISHMKYFMQL FETDETKLHQ DVMAVKDDCT NPIFCGELRY LRKKIKKDNG
TLTASDFSSD REYNLWKNYE LLEIANLMDR FEIGEKVTSH GNRLIPKDAK SVFVRLIGLV
LKKECSNAVN AINLSQEALF FFHKSARYWR IEYPSTISSL VYSAANLSVL GDEELNIPIT
ENLFSVIRNK YLCSEDNLDP SAWNAQDRYL WAANLFHTTD QSMRTINNLL TAIFSGTKPK
FSPVLSFYYS NIVGDPVMEF YETQSVAVKK YWIKLFKKTL FKASEDYFVS LLQDMLKANA
IEIQNVQNLV ETIIEAIKAI QKRYNKPLLD EISLPRQCAV FLCEVYGSDS LNLIKTAEKS
TMKMTGQKLG PIDALDMYDV LKELRQIYLQ VKPKGKFFFN LENYFIKYLT RLCDDVSRNV
QKVIKSSLES ENWQPVNDQD HFSRSVLDIF KMINESTSML EKFGWQNEFQ LAQMITVILK
AFSDGMLSYS AQLMELIQRD LQEGDEPSYS LESSDTRSSL SLNNANVNHE KSRSSRLFED
LKNVVKSTPK MVAPAPYQFK KRTCVLLNDL DKTLFLLESF EEKADPSKIS SVIAQYHSSH
NLEDNGKSFD DQNMKQVYTL RIIGAENIKG FSKTGLSNTY VSMRNITLQR EIGTTKIVAR
SITPKWDEEF VFESPFGKSN DIMFTIWHHP HSRLKNLAED DLCGKANMKF TPRKLKDDGF
PIDFSLTLNP QGTLYCQISL ESEKIDAVSS MGRIYRSFSR SRDRAINLIV NKFSDFIAFA
FSRTTLKTVC GHHGSALASD EAVYDAILPL FDYLNANLNI LASELSQRLL FMVMLRAWNL
VLENADLLLL PALNSAKVNI LRSAKKSLWE NTLSTTKTVS GYGRPLTQAE IEAVFKWLDA
LCVDFFHNKG EGPPLAELKN EYYQNILLIP AFYDKSVSEL KDEVQRLIPL YEEYLRWFYL
KKTPITFTNK SAGTISRKKS LVANIVKEPK EQLERDAEVM NIILRILIAK GQHDYVHRIL
HDRKELVNTM KNRRAVSRAV TPTGKKGRN
