YO387_YEAST
ID YO387_YEAST Reviewed; 206 AA.
AC Q08910; D6W380;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=VEL1-related protein YOR387C;
DE Flags: Precursor;
GN OrderedLocusNames=YOR387C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP SUBCELLULAR LOCATION.
RX PubMed=11935221; DOI=10.1007/s00294-001-0264-9;
RA Terashima H., Fukuchi S., Nakai K., Arisawa M., Hamada K., Yabuki N.,
RA Kitada K.;
RT "Sequence-based approach for identification of cell wall proteins in
RT Saccharomyces cerevisiae.";
RL Curr. Genet. 40:311-316(2002).
RN [5]
RP INDUCTION BY ZINC DEPLETION.
RX PubMed=14660410; DOI=10.1128/aem.69.12.7535-7540.2003;
RA Higgins V.J., Rogers P.J., Dawes I.W.;
RT "Application of genome-wide expression analysis to identify molecular
RT markers useful in monitoring industrial fermentations.";
RL Appl. Environ. Microbiol. 69:7535-7540(2003).
RN [6]
RP GLYCOSYLATION [LARGE SCALE ANALYSIS].
RX PubMed=19756047; DOI=10.1038/msb.2009.64;
RA Kung L.A., Tao S.-C., Qian J., Smith M.G., Snyder M., Zhu H.;
RT "Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals
RT new roles for protein glycosylation in eukaryotes.";
RL Mol. Syst. Biol. 5:308-308(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:11935221}.
CC -!- INDUCTION: By zinc depletion. {ECO:0000269|PubMed:14660410}.
CC -!- PTM: N-glycosylated. {ECO:0000269|PubMed:19756047}.
CC -!- SIMILARITY: Belongs to the VEL1 family. {ECO:0000305}.
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DR EMBL; Z75295; CAA99719.1; -; Genomic_DNA.
DR EMBL; AY692567; AAT92586.1; -; Genomic_DNA.
DR EMBL; BK006948; DAA11146.1; -; Genomic_DNA.
DR PIR; S67299; S67299.
DR RefSeq; NP_015032.3; NM_001183807.3.
DR AlphaFoldDB; Q08910; -.
DR BioGRID; 34768; 23.
DR DIP; DIP-5392N; -.
DR IntAct; Q08910; 1.
DR STRING; 4932.YOR387C; -.
DR PaxDb; Q08910; -.
DR EnsemblFungi; YOR387C_mRNA; YOR387C; YOR387C.
DR GeneID; 854569; -.
DR KEGG; sce:YOR387C; -.
DR SGD; S000005914; YOR387C.
DR VEuPathDB; FungiDB:YOR387C; -.
DR eggNOG; ENOG502RZUS; Eukaryota.
DR GeneTree; ENSGT00940000176668; -.
DR HOGENOM; CLU_1349595_0_0_1; -.
DR InParanoid; Q08910; -.
DR OMA; DTKNFSP; -.
DR BioCyc; YEAST:G3O-33849-MON; -.
DR PRO; PR:Q08910; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; Q08910; protein.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR InterPro; IPR019435; Vel1-like.
DR Pfam; PF10339; Vel1p; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Glycoprotein; Reference proteome; Signal; Zinc.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..206
FT /note="VEL1-related protein YOR387C"
FT /id="PRO_0000243950"
FT CARBOHYD 26
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 48
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 91
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 139
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 152
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 183
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 206 AA; 22140 MW; EDA0F117AA5D5C8D CRC64;
MSFLNIFTFF SVLVSVATAV RFDLTNVTCN NLHGPHCGTY VMEVVGQNGT FLGQSTFAGA
DVLTESAGDA WARYLGQETR FLPKLTTIAS NDTKNFSPLI FTTNIYTCNP QSIGDAMVPF
ANTVTGEIEY NSWADTADNA SFITGLANQL FNSTQYGVQV ASCYPNFASV ILSTPTVNIF
AANETLPDYC TAIQLKAVCP PDAGFA
