YOAK_ECOLI
ID YOAK_ECOLI Reviewed; 32 AA.
AC C1P602;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Uncharacterized membrane protein YoaK;
GN Name=yoaK; OrderedLocusNames=b4676, JW5292.1;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP IDENTIFICATION, SUBCELLULAR LOCATION, AND INDUCTION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=19121005; DOI=10.1111/j.1365-2958.2008.06495.x;
RA Hemm M.R., Paul B.J., Schneider T.D., Storz G., Rudd K.E.;
RT "Small membrane proteins found by comparative genomics and ribosome binding
RT site models.";
RL Mol. Microbiol. 70:1487-1501(2008).
RN [4]
RP INDUCTION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=19734316; DOI=10.1128/jb.00872-09;
RA Hemm M.R., Paul B.J., Miranda-Rios J., Zhang A., Soltanzad N., Storz G.;
RT "Small stress response proteins in Escherichia coli: proteins missed by
RT classical proteomic studies.";
RL J. Bacteriol. 192:46-58(2010).
RN [5]
RP SUBCELLULAR LOCATION, AND TOPOLOGY.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=21778229; DOI=10.1074/jbc.m111.245696;
RA Fontaine F., Fuchs R.T., Storz G.;
RT "Membrane localization of small proteins in Escherichia coli.";
RL J. Biol. Chem. 286:32464-32474(2011).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305|PubMed:19121005,
CC ECO:0000305|PubMed:21778229}; Single-pass membrane protein
CC {ECO:0000269|PubMed:19121005, ECO:0000269|PubMed:21778229}. Note=May be
CC able to insert into the membrane in both orientations. Relies on YidC
CC for insertion.
CC -!- INDUCTION: Constitutively expressed, may be induced at pH 5.5,
CC repressed by thiol oxidant diamide (at protein level).
CC {ECO:0000269|PubMed:19121005, ECO:0000269|PubMed:19734316}.
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DR EMBL; U00096; ACO59994.1; -; Genomic_DNA.
DR EMBL; AP009048; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; WP_001219350.1; NZ_STEB01000009.1.
DR RefSeq; YP_002791242.1; NC_000913.3.
DR AlphaFoldDB; C1P602; -.
DR STRING; 511145.b4676; -.
DR PaxDb; C1P602; -.
DR EnsemblBacteria; ACO59994; ACO59994; b4676.
DR GeneID; 66674318; -.
DR GeneID; 7751647; -.
DR KEGG; eco:b4676; -.
DR PATRIC; fig|511145.12.peg.1869; -.
DR eggNOG; ENOG5033FA1; Bacteria.
DR BioCyc; EcoCyc:MON0-2876; -.
DR PRO; PR:C1P602; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Stress response; Transmembrane; Transmembrane helix.
FT CHAIN 1..32
FT /note="Uncharacterized membrane protein YoaK"
FT /id="PRO_0000381983"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 32 AA; 3458 MW; EE5C2D0026FE157E CRC64;
MRIGIIFPVV IFITAVVFLA WFFIGGYAAP GA