ID   YOAL_ECOLI              Reviewed;          52 AA.
AC   P0DPP2; A0A385XJJ4;
DT   10-OCT-2018, integrated into UniProtKB/Swiss-Prot.
DT   08-MAY-2019, sequence version 2.
DT   03-AUG-2022, entry version 12.
DE   RecName: Full=Protein YoaL {ECO:0000303|PubMed:29645342};
GN   Name=yoaL {ECO:0000303|PubMed:29645342}; OrderedLocusNames=b4751;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   IDENTIFICATION, AND INDUCTION.
RX   PubMed=29645342; DOI=10.1002/pmic.201700064;
RA   VanOrsdel C.E., Kelly J.P., Burke B.N., Lein C.D., Oufiero C.E.,
RA   Sanchez J.F., Wimmers L.E., Hearn D.J., Abuikhdair F.J., Barnhart K.R.,
RA   Duley M.L., Ernst S.E.G., Kenerson B.A., Serafin A.J., Hemm M.R.;
RT   "Identifying new small proteins in Escherichia coli.";
RL   Proteomics 18:E1700064-E1700064(2018).
RN   [3]
RP   POSSIBLE FUNCTION, AND SEQUENCE REVISION TO N-TERMINUS.
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=30837344; DOI=10.1128/mbio.02819-18;
RA   Weaver J., Mohammad F., Buskirk A.R., Storz G.;
RT   "Identifying small proteins by ribosome profiling with stalled initiation
RT   complexes.";
RL   MBio 10:0-0(2019).
CC   -!- FUNCTION: May serve a regulatory role in expression of downstream gene
CC       yoaE; in a yoaL-yoaE-lacZ fusion mutation of the start codon to a stop
CC       codon in yoaL decreases expression of beta-galactosidase, suggesting
CC       translation of the 2 genes is coupled. {ECO:0000269|PubMed:30837344}.
CC   -!- INDUCTION: Expressed approximately equally in exponential and
CC       stationary phases (at protein level). {ECO:0000269|PubMed:29645342}.
CC   -!- MISCELLANEOUS: This gene lies upstream of and overlaps yoaE on the same
CC       strand in another reading frame. {ECO:0000269|PubMed:30837344}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AYC08223.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305|PubMed:29645342};
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DR   EMBL; U00096; AYC08223.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; P0DPP2; -.
DR   EnsemblBacteria; AYC08223; AYC08223; b4751.
DR   BioCyc; EcoCyc:MON0-4429; -.
DR   Proteomes; UP000000625; Chromosome.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..52
FT                   /note="Protein YoaL"
FT                   /id="PRO_0000445180"
SQ   SEQUENCE   52 AA;  6058 MW;  59D73D8DF97E8008 CRC64;
     MDRHRRHFSI RPFNACLSGT LCRTFRLHFV VTPALFLASN SYSLSRSLSW NS