YOCH_BACSU
ID YOCH_BACSU Reviewed; 287 AA.
AC O34669; Q796C6;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Cell wall-binding protein YocH;
DE Flags: Precursor;
GN Name=yocH; OrderedLocusNames=BSU19210;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.;
RT "Sequence analysis of the Bacillus subtilis chromosome region between the
RT terC and odhAB loci cloned in a yeast artificial chromosome.";
RL Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP SUBCELLULAR LOCATION, INDUCTION, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC STRAIN=168;
RX PubMed=11987133;
RX DOI=10.1002/1615-9861(200205)2:5<591::aid-prot591>3.0.co;2-8;
RA Antelmann H., Yamamoto H., Sekiguchi J., Hecker M.;
RT "Stabilization of cell wall proteins in Bacillus subtilis: a proteomic
RT approach.";
RL Proteomics 2:591-602(2002).
RN [4]
RP REGULATION BY WALR/WALK.
RX PubMed=12950927; DOI=10.1046/j.1365-2958.2003.03661.x;
RA Howell A., Dubrac S., Andersen K.K., Noone D., Fert J., Msadek T.,
RA Devine K.;
RT "Genes controlled by the essential YycG/YycF two-component system of
RT Bacillus subtilis revealed through a novel hybrid regulator approach.";
RL Mol. Microbiol. 49:1639-1655(2003).
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000269|PubMed:11987133}. Note=Released into the medium.
CC -!- INDUCTION: Positively regulated by WalR. Expressed primarily during
CC exponential growth, with levels decreasing rapidly at the beginning of
CC the stationary phase. {ECO:0000269|PubMed:11987133,
CC ECO:0000269|PubMed:12950927}.
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DR EMBL; AF027868; AAB84474.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB13813.1; -; Genomic_DNA.
DR PIR; E69901; E69901.
DR RefSeq; NP_389802.1; NC_000964.3.
DR RefSeq; WP_003231267.1; NZ_JNCM01000036.1.
DR AlphaFoldDB; O34669; -.
DR SMR; O34669; -.
DR STRING; 224308.BSU19210; -.
DR CAZy; CBM50; Carbohydrate-Binding Module Family 50.
DR PaxDb; O34669; -.
DR EnsemblBacteria; CAB13813; CAB13813; BSU_19210.
DR GeneID; 939673; -.
DR KEGG; bsu:BSU19210; -.
DR PATRIC; fig|224308.179.peg.2099; -.
DR eggNOG; COG1388; Bacteria.
DR eggNOG; COG3584; Bacteria.
DR InParanoid; O34669; -.
DR OMA; SDASNWG; -.
DR PhylomeDB; O34669; -.
DR BioCyc; BSUB:BSU19210-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0009254; P:peptidoglycan turnover; IEA:InterPro.
DR CDD; cd00118; LysM; 2.
DR Gene3D; 2.40.40.10; -; 1.
DR Gene3D; 3.10.350.10; -; 2.
DR InterPro; IPR010611; 3D_dom.
DR InterPro; IPR018392; LysM_dom.
DR InterPro; IPR036779; LysM_dom_sf.
DR InterPro; IPR036908; RlpA-like_sf.
DR Pfam; PF06725; 3D; 1.
DR Pfam; PF01476; LysM; 2.
DR SMART; SM00257; LysM; 2.
DR SUPFAM; SSF50685; SSF50685; 1.
DR SUPFAM; SSF54106; SSF54106; 2.
DR PROSITE; PS51782; LYSM; 2.
PE 1: Evidence at protein level;
KW Cell wall; Reference proteome; Repeat; Secreted; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000305"
FT CHAIN 26..287
FT /note="Cell wall-binding protein YocH"
FT /id="PRO_0000013720"
FT DOMAIN 26..69
FT /note="LysM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01118"
FT DOMAIN 78..121
FT /note="LysM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01118"
FT REGION 130..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 287 AA; 30182 MW; 7A3EBB2FD7C4B70F CRC64;
MKKTIMSFVA VAALSTTAFG AHASAKEITV QKGDTLWGIS QKNGVNLKDL KEWNKLTSDK
IIAGEKLTIS SEETTTTGQY TIKAGDTLSK IAQKFGTTVN NLKVWNNLSS DMIYAGSTLS
VKGQATAANT ATENAQTNAP QAAPKQEAVQ KEQPKQEAVQ QQPKQETKAE AETSVNTEEK
AVQSNTNNQE ASKELTVTAT AYTANDGGIS GVTATGIDLN KNPNAKVIAV DPNVIPLGSK
VYVEGYGEAT AADTGGAIKG NKIDVFVPSK SDASNWGVKT VSVKVLN
