YOD2_SCHPO
ID YOD2_SCHPO Reviewed; 457 AA.
AC Q9Y7Y9;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 101.
DE RecName: Full=Uncharacterized membrane protein C18A7.02c;
DE Flags: Precursor;
GN ORFNames=SPBC18A7.02c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the LU7TM family. {ECO:0000305}.
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DR EMBL; CU329671; CAB45934.1; -; Genomic_DNA.
DR PIR; T39751; T39751.
DR RefSeq; NP_596120.1; NM_001022038.2.
DR AlphaFoldDB; Q9Y7Y9; -.
DR BioGRID; 277367; 8.
DR STRING; 4896.SPBC18A7.02c.1; -.
DR MaxQB; Q9Y7Y9; -.
DR PaxDb; Q9Y7Y9; -.
DR EnsemblFungi; SPBC18A7.02c.1; SPBC18A7.02c.1:pep; SPBC18A7.02c.
DR GeneID; 2540850; -.
DR KEGG; spo:SPBC18A7.02c; -.
DR PomBase; SPBC18A7.02c; -.
DR VEuPathDB; FungiDB:SPBC18A7.02c; -.
DR eggNOG; KOG2568; Eukaryota.
DR HOGENOM; CLU_024065_1_0_1; -.
DR InParanoid; Q9Y7Y9; -.
DR OMA; VNWQNAY; -.
DR PhylomeDB; Q9Y7Y9; -.
DR PRO; PR:Q9Y7Y9; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; ISM:PomBase.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; ISM:PomBase.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; ISM:PomBase.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IBA:GO_Central.
DR InterPro; IPR009637; GPR107/GPR108-like.
DR PANTHER; PTHR21229; PTHR21229; 1.
DR Pfam; PF06814; Lung_7-TM_R; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Membrane; Receptor; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..457
FT /note="Uncharacterized membrane protein C18A7.02c"
FT /id="PRO_0000339415"
FT TOPO_DOM 19..173
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 195..207
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 229..243
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 265..284
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 285..305
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 306..314
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 336..358
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 359..379
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 380..457
FT /note="Lumenal"
FT /evidence="ECO:0000255"
SQ SEQUENCE 457 AA; 52862 MW; 61257C6884669FB7 CRC64;
MKLLISLLWS IFFSIVYSEK TLLNFKHYEL CNGIYSKSES GGSLNPAIYV NWTEPWGQED
EVEVLIFNWK EIRKLGAFRS DDQFTYICDY DAVYTDHLCE ADQLGLYLWN STSAKSIRSY
IIPTNADPQN IIYEISQSGY YCIWSHSKKM LPYQALVNWQ NAYGGLPASQ FPRMPISGGI
TIAYSVILAL WMFFRFQYKH SIVTVQKAIM FLLIFSCAQQ AVTSIVLDTE NLRNRGNFTW
LGETLVSILF ACQLVLDLAL LLILSWGYTR YSTNMRDRLF TEAKIPLIIC FFALFVVRFF
AITIQSIHLG LWFCFFFLTA CISALYILFG AFVALPSTLR ALVEQRYYTL HSIYKIFRIM
VLCGVVTIFS FSLVALIFCS NTNNNSTNKL WKIRWYFLDG WIDGVHLTYL ITLSSLWRPS
QENPDLDPTG LSYPVLDPRL EEELDLLEED IRADKSK
