ID   YOFA_BACVZ              Reviewed;         288 AA.
AC   A7Z5E4;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=HTH-type transcriptional regulator YofA;
GN   Name=yofA; OrderedLocusNames=RBAM_018580;
OS   Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)
OS   (Bacillus amyloliquefaciens subsp. plantarum).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus amyloliquefaciens group.
OX   NCBI_TaxID=326423;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42;
RX   PubMed=17704766; DOI=10.1038/nbt1325;
RA   Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K.,
RA   Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H.,
RA   Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H.,
RA   Strittmatter A., Gottschalk G., Borriss R.;
RT   "Comparative analysis of the complete genome sequence of the plant growth-
RT   promoting bacterium Bacillus amyloliquefaciens FZB42.";
RL   Nat. Biotechnol. 25:1007-1014(2007).
CC   -!- FUNCTION: Regulates expression of the cell division protein ftsW, and
CC       is essential for cell viability during stationary phase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; CP000560; ABS74220.1; -; Genomic_DNA.
DR   RefSeq; WP_012117710.1; NC_009725.2.
DR   AlphaFoldDB; A7Z5E4; -.
DR   SMR; A7Z5E4; -.
DR   STRING; 326423.RBAM_018580; -.
DR   EnsemblBacteria; ABS74220; ABS74220; RBAM_018580.
DR   KEGG; bay:RBAM_018580; -.
DR   HOGENOM; CLU_039613_6_1_9; -.
DR   OMA; MEMESYH; -.
DR   Proteomes; UP000001120; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; DNA-binding; Septation;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..288
FT                   /note="HTH-type transcriptional regulator YofA"
FT                   /id="PRO_0000337972"
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   288 AA;  32392 MW;  1641CE445732A54C CRC64;
     MESGDLKIFQ AVARKGSISK AAESLHYVQS NVTNRIQQLE RQLQTQLFYR TNRGMTLTPA
     GENLLKDADR ILQLLHEAQK TAQEAGDPNG PLRIGSLETA AAVHLPQFFT EYCSRYPKVQ
     LSLSTGDTHT LVQHILHYEL DGAFVYGPVE YEDLEQVAVF QEELVLASNK REGSLQDLLR
     EPILYFAAGC SHRRKIKNIL KEEAVPAHKI IEFGTLEAII GAVQAGMGVS FLPASAVRYF
     QNRKNLFLHE LPEQFRDMNI SFIYQSDLFL TSAFEELLNG LKALPNGR