ID   YOGA_BACSU              Reviewed;         329 AA.
AC   O35017;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Uncharacterized zinc-type alcohol dehydrogenase-like protein YogA;
DE            EC=1.-.-.-;
GN   Name=yogA; OrderedLocusNames=BSU18430;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   DISRUPTION PHENOTYPE.
RC   STRAIN=168 / CU1065;
RX   PubMed=10960106; DOI=10.1128/jb.182.18.5202-5210.2000;
RA   Turner M.S., Helmann J.D.;
RT   "Mutations in multidrug efflux homologs, sugar isomerases, and
RT   antimicrobial biosynthesis genes differentially elevate activity of the
RT   sigma(X) and sigma(W) factors in Bacillus subtilis.";
RL   J. Bacteriol. 182:5202-5210(2000).
CC   -!- DISRUPTION PHENOTYPE: Cells lacking this gene show up-regulated sigma X
CC       activity. {ECO:0000269|PubMed:10960106}.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. Quinone oxidoreductase subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL009126; CAB13726.1; -; Genomic_DNA.
DR   PIR; F69905; F69905.
DR   RefSeq; NP_389725.1; NC_000964.3.
DR   RefSeq; WP_004399251.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O35017; -.
DR   SMR; O35017; -.
DR   STRING; 224308.BSU18430; -.
DR   PaxDb; O35017; -.
DR   PRIDE; O35017; -.
DR   EnsemblBacteria; CAB13726; CAB13726; BSU_18430.
DR   GeneID; 940019; -.
DR   KEGG; bsu:BSU18430; -.
DR   PATRIC; fig|224308.179.peg.2010; -.
DR   eggNOG; COG0604; Bacteria.
DR   InParanoid; O35017; -.
DR   OMA; LNHHDLW; -.
DR   PhylomeDB; O35017; -.
DR   BioCyc; BSUB:BSU18430-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; SSF50129; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..329
FT                   /note="Uncharacterized zinc-type alcohol dehydrogenase-like
FT                   protein YogA"
FT                   /id="PRO_0000379127"
SQ   SEQUENCE   329 AA;  35811 MW;  4F2452EAACAFFA28 CRC64;
     MKAVIHNGKA GLLGLSVQDV PSTKPGYGEV KVKLKSAGLN HRDLFLMKNK SEQDPHMILG
     SDGAGIIEEI GEGVKNVTVQ TEVVIFPTLN WDLTENVPPV PEILGGPSDG TLAEYVIIPS
     QNAIKKPAYL SWEEAGVLPL SALTAYRALF TKGQLKKGEH LLIPGIGSGV ATYALFMAKA
     IGATVSVTSR SEEKRKKALK LGADYAFDSY SNWDEQLQGK KIDVVLDSIG PALFSEYFRH
     VKPNGRIVSF GASSGDNLSF PVRSLFFPQV NVLGTSMGSG EEFQAMLAFI DKHKLRPVID
     RIYPLEKACE AYKRMQEGRQ FGNIGIVME