ID   YOHC_ECOL6              Reviewed;         195 AA.
AC   P0AD18; P33365;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Inner membrane protein YohC;
GN   Name=yohC; OrderedLocusNames=c2667;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN81123.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE014075; AAN81123.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_001295454.1; NC_004431.1.
DR   AlphaFoldDB; P0AD18; -.
DR   SMR; P0AD18; -.
DR   STRING; 199310.c2667; -.
DR   EnsemblBacteria; AAN81123; AAN81123; c2667.
DR   GeneID; 66673969; -.
DR   KEGG; ecc:c2667; -.
DR   eggNOG; ENOG502Z7KS; Bacteria.
DR   HOGENOM; CLU_099801_0_0_6; -.
DR   OMA; HPKEEWH; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006977; Yip1_dom.
DR   Pfam; PF04893; Yip1; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..195
FT                   /note="Inner membrane protein YohC"
FT                   /id="PRO_0000169139"
FT   TOPO_DOM        1..32
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        56..64
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        88..107
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        131..134
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        158..169
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        170..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        193..195
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   195 AA;  21691 MW;  87B3B5437D6D56E8 CRC64;
     MSHVWGLFSH PDREMQVINR ENETISHHYT HHVLLMAAIP VICAFIGTTQ IGWNFGDGTI
     LKLSWFTGLA LAVLFYGVML AGVAVMGRVI WWMARNYPQR PSLAHCMVFA GYVATPLFLS
     GLVALYPLVW LCALVGTVAL FYTGYLLYLG IPSFLNINKE EGLSFSSSTL AIGVLVLEVL
     LALTVILWGY GYRLF