YOHC_ECOLI
ID YOHC_ECOLI Reviewed; 195 AA.
AC P0AD17; P33365; Q2MAU4;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Inner membrane protein YohC;
GN Name=yohC; OrderedLocusNames=b2135, JW5356;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / BHB2600;
RA Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K.,
RA Church G.M.;
RT "Automated multiplex sequencing of the E.coli genome.";
RL Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA60497.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; U00007; AAA60497.1; ALT_INIT; Genomic_DNA.
DR EMBL; U00096; AAC75196.2; -; Genomic_DNA.
DR EMBL; AP009048; BAE76612.1; -; Genomic_DNA.
DR RefSeq; NP_416639.2; NC_000913.3.
DR RefSeq; WP_001295454.1; NZ_SSZK01000011.1.
DR AlphaFoldDB; P0AD17; -.
DR SMR; P0AD17; -.
DR BioGRID; 4261820; 8.
DR BioGRID; 851008; 2.
DR IntAct; P0AD17; 2.
DR STRING; 511145.b2135; -.
DR PaxDb; P0AD17; -.
DR PRIDE; P0AD17; -.
DR EnsemblBacteria; AAC75196; AAC75196; b2135.
DR EnsemblBacteria; BAE76612; BAE76612; BAE76612.
DR GeneID; 66673969; -.
DR GeneID; 946666; -.
DR KEGG; ecj:JW5356; -.
DR KEGG; eco:b2135; -.
DR PATRIC; fig|1411691.4.peg.107; -.
DR EchoBASE; EB1953; -.
DR eggNOG; ENOG502Z7KS; Bacteria.
DR HOGENOM; CLU_099801_0_0_6; -.
DR InParanoid; P0AD17; -.
DR OMA; HPKEEWH; -.
DR PhylomeDB; P0AD17; -.
DR BioCyc; EcoCyc:EG12016-MON; -.
DR PRO; PR:P0AD17; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:EcoliWiki.
DR InterPro; IPR006977; Yip1_dom.
DR Pfam; PF04893; Yip1; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..195
FT /note="Inner membrane protein YohC"
FT /id="PRO_0000169138"
FT TOPO_DOM 1..32
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 33..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 56..64
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 88..107
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 108..130
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 131..134
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 158..169
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 170..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 193..195
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 195 AA; 21691 MW; 87B3B5437D6D56E8 CRC64;
MSHVWGLFSH PDREMQVINR ENETISHHYT HHVLLMAAIP VICAFIGTTQ IGWNFGDGTI
LKLSWFTGLA LAVLFYGVML AGVAVMGRVI WWMARNYPQR PSLAHCMVFA GYVATPLFLS
GLVALYPLVW LCALVGTVAL FYTGYLLYLG IPSFLNINKE EGLSFSSSTL AIGVLVLEVL
LALTVILWGY GYRLF
