ID   YOHJ_ECOLI              Reviewed;         132 AA.
AC   P60632; P33372; Q2MAT8;
DT   15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2004, sequence version 2.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=UPF0299 membrane protein YohJ;
GN   Name=yohJ; OrderedLocusNames=b2141, JW2129;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / BHB2600;
RA   Richterich P., Lakey N., Gryan G., Jaehn L., Mintz L., Robison K.,
RA   Church G.M.;
RT   "Automated multiplex sequencing of the E.coli genome.";
RL   Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the UPF0299 family. {ECO:0000305}.
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DR   EMBL; U00007; AAA60504.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC75202.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76618.1; -; Genomic_DNA.
DR   PIR; D64982; D64982.
DR   RefSeq; NP_416646.1; NC_000913.3.
DR   RefSeq; WP_001295452.1; NZ_STEB01000002.1.
DR   AlphaFoldDB; P60632; -.
DR   SMR; P60632; -.
DR   BioGRID; 4262175; 7.
DR   IntAct; P60632; 1.
DR   STRING; 511145.b2141; -.
DR   PaxDb; P60632; -.
DR   PRIDE; P60632; -.
DR   EnsemblBacteria; AAC75202; AAC75202; b2141.
DR   EnsemblBacteria; BAE76618; BAE76618; BAE76618.
DR   GeneID; 58388960; -.
DR   GeneID; 949127; -.
DR   KEGG; ecj:JW2129; -.
DR   KEGG; eco:b2141; -.
DR   PATRIC; fig|1411691.4.peg.101; -.
DR   EchoBASE; EB1958; -.
DR   eggNOG; COG1380; Bacteria.
DR   HOGENOM; CLU_113736_1_1_6; -.
DR   InParanoid; P60632; -.
DR   OMA; MSVMFIP; -.
DR   PhylomeDB; P60632; -.
DR   BioCyc; EcoCyc:EG12023-MON; -.
DR   PRO; PR:P60632; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; ISM:EcoCyc.
DR   HAMAP; MF_01144; UPF0299; 1.
DR   InterPro; IPR005538; LrgA/CidA.
DR   InterPro; IPR022957; Uncharacterised_UPF0299.
DR   PANTHER; PTHR33931; PTHR33931; 1.
DR   Pfam; PF03788; LrgA; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..132
FT                   /note="UPF0299 membrane protein YohJ"
FT                   /id="PRO_0000072806"
FT   TOPO_DOM        1..6
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        28..30
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        52..62
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        84..92
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        114..132
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   132 AA;  14579 MW;  263DA3254DEF81A8 CRC64;
     MSKTLNIIWQ YLRAFVLIYA CLYAGIFIAS LLPVTIPGSI IGMLILFVLL ALQILPAKWV
     NPGCYVLIRY MALLFVPIGV GVMQYFDLLR AQFGPVVVSC AVSTLVVFLV VSWSSQLVHG
     ERKVVGQKGS EE