YOHP_ECOLI
ID YOHP_ECOLI Reviewed; 27 AA.
AC C1P609;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 1.
DT 03-AUG-2022, entry version 46.
DE RecName: Full=Uncharacterized membrane protein YohP;
GN Name=yohP; OrderedLocusNames=b4679, JW5358.1;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP IDENTIFICATION, SUBCELLULAR LOCATION, AND INDUCTION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=19121005; DOI=10.1111/j.1365-2958.2008.06495.x;
RA Hemm M.R., Paul B.J., Schneider T.D., Storz G., Rudd K.E.;
RT "Small membrane proteins found by comparative genomics and ribosome binding
RT site models.";
RL Mol. Microbiol. 70:1487-1501(2008).
RN [4]
RP INDUCTION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=19734316; DOI=10.1128/jb.00872-09;
RA Hemm M.R., Paul B.J., Miranda-Rios J., Zhang A., Soltanzad N., Storz G.;
RT "Small stress response proteins in Escherichia coli: proteins missed by
RT classical proteomic studies.";
RL J. Bacteriol. 192:46-58(2010).
RN [5]
RP SUBCELLULAR LOCATION, TOPOLOGY, AND MUTAGENESIS OF LYS-2 AND LYS-24.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=21778229; DOI=10.1074/jbc.m111.245696;
RA Fontaine F., Fuchs R.T., Storz G.;
RT "Membrane localization of small proteins in Escherichia coli.";
RL J. Biol. Chem. 286:32464-32474(2011).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305|PubMed:19121005,
CC ECO:0000305|PubMed:21778229}; Single-pass membrane protein
CC {ECO:0000269|PubMed:19121005, ECO:0000269|PubMed:21778229}. Note=May be
CC able to insert into the membrane in both orientations. Depletion of
CC SecE or YidC does not affect membrane insertion.
CC -!- INDUCTION: Expressed in exponential phase, strongly induced in
CC stationary phase (PubMed:19121005) and in minimal glucose or glycerol
CC medium, in low oxygen, by SDS/EDTA (envelope stress) and by H(2)O(2)
CC (PubMed:19734316) (at protein level). {ECO:0000269|PubMed:19121005,
CC ECO:0000269|PubMed:19734316}.
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DR EMBL; U00096; ACO60001.1; -; Genomic_DNA.
DR EMBL; AP009048; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; WP_000691708.1; NZ_STEB01000002.1.
DR RefSeq; YP_002791249.1; NC_000913.3.
DR AlphaFoldDB; C1P609; -.
DR STRING; 511145.b4679; -.
DR PaxDb; C1P609; -.
DR PRIDE; C1P609; -.
DR EnsemblBacteria; ACO60001; ACO60001; b4679.
DR GeneID; 60373675; -.
DR GeneID; 66673965; -.
DR GeneID; 7751636; -.
DR KEGG; eco:b4679; -.
DR PATRIC; fig|83333.103.peg.3008; -.
DR BioCyc; EcoCyc:MON0-2879; -.
DR PRO; PR:C1P609; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Stress response; Transmembrane; Transmembrane helix.
FT CHAIN 1..27
FT /note="Uncharacterized membrane protein YohP"
FT /id="PRO_0000381986"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MUTAGEN 2
FT /note="K->G: Protein mostly C-terminus inside. Both
FT orientations found; when associated with 24-G."
FT /evidence="ECO:0000269|PubMed:21778229"
FT MUTAGEN 24
FT /note="K->G: Protein mostly C-terminus outside. Both
FT orientations found; when associated with 2-G."
FT /evidence="ECO:0000269|PubMed:21778229"
SQ SEQUENCE 27 AA; 3092 MW; C48BF16B085ADF08 CRC64;
MKIILWAVLI IFLIGLLVVT GVFKMIF
