YOL4_SCHPO
ID YOL4_SCHPO Reviewed; 675 AA.
AC Q9P7P0;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Uncharacterized acyltransferase C1718.04;
DE EC=2.3.-.-;
GN ORFNames=SPBC1718.04;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-669, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC acyltransferase family. {ECO:0000305}.
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DR EMBL; CU329671; CAB75994.1; -; Genomic_DNA.
DR PIR; T50332; T50332.
DR RefSeq; NP_596450.1; NM_001022369.2.
DR AlphaFoldDB; Q9P7P0; -.
DR SMR; Q9P7P0; -.
DR STRING; 4896.SPBC1718.04.1; -.
DR iPTMnet; Q9P7P0; -.
DR MaxQB; Q9P7P0; -.
DR PaxDb; Q9P7P0; -.
DR PRIDE; Q9P7P0; -.
DR EnsemblFungi; SPBC1718.04.1; SPBC1718.04.1:pep; SPBC1718.04.
DR GeneID; 2540110; -.
DR KEGG; spo:SPBC1718.04; -.
DR PomBase; SPBC1718.04; -.
DR VEuPathDB; FungiDB:SPBC1718.04; -.
DR eggNOG; ENOG502QQ2N; Eukaryota.
DR HOGENOM; CLU_007860_1_0_1; -.
DR InParanoid; Q9P7P0; -.
DR OMA; NIRDHQV; -.
DR PhylomeDB; Q9P7P0; -.
DR PRO; PR:Q9P7P0; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity; ISO:PomBase.
DR GO; GO:0016287; F:glycerone-phosphate O-acyltransferase activity; IBA:GO_Central.
DR GO; GO:0008654; P:phospholipid biosynthetic process; ISO:PomBase.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
PE 1: Evidence at protein level;
KW Acyltransferase; Endoplasmic reticulum; Membrane; Phosphoprotein;
KW Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..675
FT /note="Uncharacterized acyltransferase C1718.04"
FT /id="PRO_0000317313"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 397..417
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 448..468
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 481..501
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 616..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 669
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 675 AA; 76628 MW; 388E126EDC7A57E8 CRC64;
MQHTFIYDTC LWILSILIDF FFREVKTRGS FRVPRKGPLI LVAAPHANQF VDPLILMLQL
RREVGRRTSI LVAAKSYRQR FIGLMSRAFG AIPVERAQDL AIRGEGKIFV VAEGDKTAIH
GKDTLFTKHS VGDTLLLPNN YGSSHIASIK SDTLLYVKRE FRGEDAERVL LSPEGSSYKV
APEIDQTYVY NEVRRRLVKG ACIALFPEGG SHDRPEMLPL KAGVAIMALE TLSQHPDCGL
QLLPCGMNYF HPHRFRSRAV LEFGSPLSIP TEYVELYKAK KRREAIQGVL DMIYDALLSV
TVQAPDYETL MVIQACRRLY KPAHIQFALP KVVDLNRKLI VGYNHFKHDP RVIRLHDKIL
LYNRQLYRLG LRDHQVQSLQ YSRFMILYKL VYRCCKLFLL ALGALPGAIL FSPVFIAAHR
ISVKKAAAAL KASSVKIQGR DILATWKLLV ALGMTPILYS FYALLCCYYI YSYKLIPHSS
IFVYTVPIIS TFLFPMVTYA ALRFGEVAVD IYKSIRPLFL ALIPSKANAV YILKDERKQL
VAEVTDLINK LGPELFPDFD PDRITTTIEK PERPSRFARR LSSSVASDVD NLSQLHDTDL
NSEVSAPAPL QNVYLYSPNP SALPPSDEEE KDINDKAKLI RNALRQRMGQ RMTEIRSRDT
PPEEVFSESD EELSD
