YON8_SCHPO
ID YON8_SCHPO Reviewed; 629 AA.
AC Q9Y819;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Transmembrane 9 superfamily protein C1105.08;
DE Flags: Precursor;
GN ORFNames=SPBC1105.08;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}. Vacuole membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
CC {ECO:0000305}.
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DR EMBL; CU329671; CAB50971.1; -; Genomic_DNA.
DR PIR; T39285; T39285.
DR RefSeq; NP_596464.1; NM_001022383.2.
DR AlphaFoldDB; Q9Y819; -.
DR BioGRID; 276693; 28.
DR STRING; 4896.SPBC1105.08.1; -.
DR MaxQB; Q9Y819; -.
DR PaxDb; Q9Y819; -.
DR PRIDE; Q9Y819; -.
DR EnsemblFungi; SPBC1105.08.1; SPBC1105.08.1:pep; SPBC1105.08.
DR GeneID; 2540158; -.
DR KEGG; spo:SPBC1105.08; -.
DR PomBase; SPBC1105.08; -.
DR VEuPathDB; FungiDB:SPBC1105.08; -.
DR eggNOG; KOG1278; Eukaryota.
DR HOGENOM; CLU_010714_4_1_1; -.
DR InParanoid; Q9Y819; -.
DR OMA; CYPKNGT; -.
DR PhylomeDB; Q9Y819; -.
DR PRO; PR:Q9Y819; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0010008; C:endosome membrane; ISO:PomBase.
DR GO; GO:0000329; C:fungal-type vacuole membrane; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0016197; P:endosomal transport; ISO:PomBase.
DR GO; GO:0072657; P:protein localization to membrane; IBA:GO_Central.
DR GO; GO:0007034; P:vacuolar transport; IBA:GO_Central.
DR InterPro; IPR004240; EMP70.
DR PANTHER; PTHR10766; PTHR10766; 1.
DR Pfam; PF02990; EMP70; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix; Vacuole.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..629
FT /note="Transmembrane 9 superfamily protein C1105.08"
FT /id="PRO_0000315979"
FT TOPO_DOM 27..266
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 267..287
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 288..337
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 359..364
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 365..385
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 386..401
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 423..436
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 437..457
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 458..488
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 489..509
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 510..519
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 520..544
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 545..558
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 559..579
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 580..598
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 599..619
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 620..629
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT CARBOHYD 157
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 629 AA; 71131 MW; AC138984B757EAC2 CRC64;
MLLPSIPSCS FSFVVFVSVL LQTCFSFQLT PLSPKNYPPG ASIDTTVNTI SPFIGDGRGS
DIFNYEYYDE RFHFCRPENI AKQSESLGSV LFGDRLYNSP IEIKMLENQD CVPLCASIIP
SSDVSFIRDL ISKNYVVNWN IDNLPVATYL EGTNSKNYSL SPGFPLGKNT EKGVILFNHY
DIVIEYHTTS SDQHRVVGAY VKPVSKESTL VDGNPVCSSS SNPQYLPEGA DLTLVTSYSV
SWKYSDTPWA TRWDKYMHIE SRQIRWIFII HSAIIDTFLI FVVSIILYRT LNRDINKYNS
AFVDQEDVQE DFGWKLVHGD VFRPPRRPML FSILLGTGAQ LLFMSSGIVL FAIFGIVAPS
RRGSLATATV ALFIISGFVS GYVSALSYKL MQGMLRKRNL LLTPFVVPGF MLAAALFFNM
VFWSKSSSST VPFSSWLLLI FLYLLFTVPL SFVGSLIGFR SREFVPPVRT NQIPRQIPSH
SIWLSSFPSA IIGGSIPFLV ILIELFSILD SLWFHPLYFM FGFSFFCFGI LVTTCIMVSI
ITVYFQLCSE NYNWWWRSFI TPGFCGIYVF IFSVFYWFFK ISSSSLATAV LYFGYSLLIS
VLVFFLCGSV GFFGAFLFVN KIYASIKID
