ID   YORK_BACSU              Reviewed;         576 AA.
AC   O31903;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Putative SPbeta prophage-derived single-strand DNA-specific exonuclease YorK;
DE            EC=3.1.-.-;
GN   Name=yorK; OrderedLocusNames=BSU20350;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-473, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RC   STRAIN=168;
RX   PubMed=17218307; DOI=10.1074/mcp.m600464-mcp200;
RA   Macek B., Mijakovic I., Olsen J.V., Gnad F., Kumar C., Jensen P.R.,
RA   Mann M.;
RT   "The serine/threonine/tyrosine phosphoproteome of the model bacterium
RT   Bacillus subtilis.";
RL   Mol. Cell. Proteomics 6:697-707(2007).
CC   -!- FUNCTION: Putative single-stranded-DNA-specific exonuclease.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the RecJ family. {ECO:0000305}.
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DR   EMBL; AL009126; CAB13927.1; -; Genomic_DNA.
DR   RefSeq; NP_389917.1; NC_000964.3.
DR   RefSeq; WP_004399433.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; O31903; -.
DR   SMR; O31903; -.
DR   STRING; 224308.BSU20350; -.
DR   iPTMnet; O31903; -.
DR   PaxDb; O31903; -.
DR   PRIDE; O31903; -.
DR   EnsemblBacteria; CAB13927; CAB13927; BSU_20350.
DR   GeneID; 939545; -.
DR   KEGG; bsu:BSU20350; -.
DR   PATRIC; fig|224308.179.peg.2225; -.
DR   eggNOG; COG0608; Bacteria.
DR   OMA; CNGIDEP; -.
DR   PhylomeDB; O31903; -.
DR   BioCyc; BSUB:BSU20350-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0008409; F:5'-3' exonuclease activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   InterPro; IPR001667; DDH_dom.
DR   InterPro; IPR038763; DHH_sf.
DR   InterPro; IPR004610; RecJ.
DR   InterPro; IPR041122; RecJ_OB.
DR   Pfam; PF01368; DHH; 1.
DR   Pfam; PF17768; RecJ_OB; 1.
DR   SUPFAM; SSF64182; SSF64182; 1.
DR   TIGRFAMs; TIGR00644; recJ; 1.
PE   1: Evidence at protein level;
KW   Exonuclease; Hydrolase; Nuclease; Phosphoprotein; Reference proteome.
FT   CHAIN           1..576
FT                   /note="Putative SPbeta prophage-derived single-strand DNA-
FT                   specific exonuclease YorK"
FT                   /id="PRO_0000360577"
FT   MOD_RES         473
FT                   /note="Phosphotyrosine"
FT                   /evidence="ECO:0000269|PubMed:17218307"
SQ   SEQUENCE   576 AA;  65774 MW;  68F1007CC9D8D157 CRC64;
     MEYRLIGDND YNFDPLATIL KNRGIEDPKL FVNVDQSSVI HYSKLNNIDK AADCLIRHLN
     NKNKLFVQVD SDVDGYTSSS IIINYIKKIC PKANIHYRIQ DGKEHGIFID TIPDDVDLVI
     IPDAGSSQFE EHEALNKRGT EIIVIDHHEC ERVSEHAIVV NNQLSPNYSN KTLTGAGMAY
     KFCQAIDEKL NKNEAEQFLD LVSIGNIADS ADSRNLETRY FMNEGLKKIK HPLLKKLFKK
     QEFSTKGDKS IQNTQFFINP LINAAIRVGS SEEKDQMMRA FLLSKEKVPY KKRGQSETEL
     VSIHEDTVRI LGNLKAKQKR IVDAAGVEIK NRIEEKSLTA NKVLIVYIEG ILDKSLTGLV
     ANQLAEEYKK PVLLARNDPE KGKDILSGSI RGYDKGFIKD FKKELIDTGL FEFVEGHPNA
     AGFAIKRQNL ILVNKVLNEK FKDINIEEDI QNVDFEIPAK RLRKEFILQL DGYKDYWGYK
     VEEPLIAITD LEIEVEQIEH LGKKNKTTVK FKHGDIEYIR FKSDENYFNQ LTASNGTLVI
     NVIGKAKANE YKGKKTPQIE IYELEVVRTK QKELVF