YORN_SCHPO
ID YORN_SCHPO Reviewed; 673 AA.
AC O94271; Q9UU59;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Uncharacterized RING finger protein P8B7.23;
GN ORFNames=SPBP8B7.23;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 33-159, AND SUBCELLULAR
RP LOCATION.
RC STRAIN=ATCC 38364 / 968;
RX PubMed=10759889; DOI=10.1046/j.1365-2443.2000.00317.x;
RA Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T.,
RA Hiraoka Y.;
RT "Large-scale screening of intracellular protein localization in living
RT fission yeast cells by the use of a GFP-fusion genomic DNA library.";
RL Genes Cells 5:169-190(2000).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
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DR EMBL; CU329671; CAA21808.1; -; Genomic_DNA.
DR EMBL; AB027798; BAA87102.1; -; Genomic_DNA.
DR PIR; T40817; T40817.
DR RefSeq; NP_596530.1; NM_001022451.2.
DR AlphaFoldDB; O94271; -.
DR BioGRID; 277876; 11.
DR STRING; 4896.SPBP8B7.23.1; -.
DR iPTMnet; O94271; -.
DR MaxQB; O94271; -.
DR PaxDb; O94271; -.
DR EnsemblFungi; SPBP8B7.23.1; SPBP8B7.23.1:pep; SPBP8B7.23.
DR GeneID; 2541365; -.
DR KEGG; spo:SPBP8B7.23; -.
DR PomBase; SPBP8B7.23; -.
DR VEuPathDB; FungiDB:SPBP8B7.23; -.
DR eggNOG; KOG2164; Eukaryota.
DR HOGENOM; CLU_011811_1_0_1; -.
DR InParanoid; O94271; -.
DR OMA; PCLLHYL; -.
DR PhylomeDB; O94271; -.
DR PRO; PR:O94271; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0061659; F:ubiquitin-like protein ligase activity; ISM:PomBase.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0070647; P:protein modification by small protein conjugation or removal; IC:PomBase.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR039739; Mag2/Rnf10.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12983; PTHR12983; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Cytoplasm; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..673
FT /note="Uncharacterized RING finger protein P8B7.23"
FT /id="PRO_0000310492"
FT ZN_FING 214..273
FT /note="RING-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..61
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..87
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 673 AA; 76460 MW; 7317BDAD768FC883 CRC64;
MLNGEKSALG EMPSNSNSSS KLNAKSPNFI PSSSNIPRSS AKTKEHSADR KPHRNSEKKT
QGMPRKNQQL ASSERKTKNK KRLEKQSSAI ADSIGESLDD PQTVYDEHLF DILSARTNKR
GQINLNHLLN FQFTPRTNSN AFSAPPRRSR GYNTYGQGSG HHPMDKSRYV NANYRFVVSP
IGDYQSQKLD PDSPVKWEDV WQVLCSSDFQ LAACPFCLEE KPVAARMSRC GHVYCFSCLL
RFVETPTAAE VKAAETSGTK IVKCGHRSCP ICWDSIRLRD VHPIRWVEDK EFQKLEEGKS
VCLRLYQRNN GSILAFPRSC RSFALDGSFH SDEIPNFTMS GAAYARIIIG SHDYMVQQHL
LEIEQLQQIA AEDISLYGSA DTYYERITQI LLDRISSLSE SVNEQNIKSL QTDIDNLCLQ
SNSLKQLSEV DDLNDVSGSE IADAYLFYQP FAHSHIYLSP LDIRILKSAF GSYENFPDEL
VPRVERISSG HLVNSELRQR FKYMAHLPEG CEVAFIECDW SKIIPKEVLL TFKSEISKRR
KQRKAQEMRE ERYRQRAERD TEEQIYSELN MQRPVPKTVV HEDPAEAFPT LGSHHQFEST
DEVNTDESTL STAKTVWGTR ALANIQNDTD DQDDLDGWKV DWDKVAQLSA PSKNSKNKKK
KKLVLLSTGA AHR