ID   YOS3_SCHPO              Reviewed;         692 AA.
AC   Q9P7M0;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2012, sequence version 2.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=ABC1 family protein C21C3.03, mitochondrial;
DE   Flags: Precursor;
GN   ORFNames=SPBC21C3.03;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   REVISION OF GENE MODEL.
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane
CC       {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. ADCK protein
CC       kinase family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB76039.2; -; Genomic_DNA.
DR   PIR; T50347; T50347.
DR   RefSeq; NP_596583.2; NM_001022503.2.
DR   AlphaFoldDB; Q9P7M0; -.
DR   BioGRID; 276824; 21.
DR   STRING; 4896.SPBC21C3.03.1; -.
DR   MaxQB; Q9P7M0; -.
DR   PaxDb; Q9P7M0; -.
DR   EnsemblFungi; SPBC21C3.03.1; SPBC21C3.03.1:pep; SPBC21C3.03.
DR   GeneID; 2540293; -.
DR   KEGG; spo:SPBC21C3.03; -.
DR   PomBase; SPBC21C3.03; -.
DR   VEuPathDB; FungiDB:SPBC21C3.03; -.
DR   eggNOG; KOG1236; Eukaryota.
DR   HOGENOM; CLU_006533_6_0_1; -.
DR   InParanoid; Q9P7M0; -.
DR   OMA; RRDLKIM; -.
DR   PRO; PR:Q9P7M0; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031966; C:mitochondrial membrane; IC:PomBase.
DR   GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR   GO; GO:0016301; F:kinase activity; ISM:PomBase.
DR   CDD; cd13971; ADCK2-like; 1.
DR   InterPro; IPR004147; ABC1_dom.
DR   InterPro; IPR044095; ADCK2_dom.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   Pfam; PF03109; ABC1; 2.
DR   SUPFAM; SSF56112; SSF56112; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Reference proteome; Transit peptide;
KW   Transmembrane; Transmembrane helix.
FT   TRANSIT         1..91
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           92..692
FT                   /note="ABC1 family protein C21C3.03, mitochondrial"
FT                   /id="PRO_0000310292"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   692 AA;  79369 MW;  326AAA72B41E9085 CRC64;
     MISFSHWNSH IRSGLSLSMI PSANSRFAFI IQRNYIPVVN SQNTRWKRLC GTQSVWSPYK
     KKHVLVNRLK HISLFPKPIF ARKFTTRQKS EDQKQWRILR ITFLVLPFTV GGLWILYRVK
     NRKNNIFSFD ELELEERSNR PRSIFGKIKQ FFNILLRSFN LFIIFSPIII TLPFIALISF
     LHLRSLSSLT VSIWLRFLVT QLERAGATFI KLGQWAASRT DLFPPAFCKT LSKLHSHVTP
     HSLAYTQSVI CKTYKVESIE EIFVNFNPIP IGVGAIAQVY TATIKKAATQ QDNSYFTSML
     QSIGFRQKNI SDAPVTQDVA IKVLHPNVEK YISLDLQILG FFAKLINLVP SMKWLSLPDE
     VKVFGAMLNQ QLNLHYEALH LNQFRLNFRG NRYVEFPAPY DDYTTNQILL EDYMPGIPLS
     AFLKHKSGPF NKLLANTGNN ALFQMLIVDN FTHADLHPGN VLVKFYKGIP KTIFNQDNEI
     NDSIYKILST CSTEEWDSAM EELNILGYRP TLVFLDAGLV TKLSTQDQKN FLDLFQAVLT
     FHGYEAGLLM VERSRQTERV INKDIFALKM EHLLNEIQKS TLSLKSLQIG TILQEVMTMA
     REHHVRIEAN FANTVLSILL VEGAGRQLYP EMDLLSNATP YLRSASSKSN VSLTNPMVQL
     WIALEARQFL LLSTSKETVE KWVKSDMIAP NI