YOW4_SCHPO
ID YOW4_SCHPO Reviewed; 1014 AA.
AC Q9USY2;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 134.
DE RecName: Full=Uncharacterized RNA-binding protein C1861.04c;
GN ORFNames=SPBC1861.04c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAB52740.1; -; Genomic_DNA.
DR PIR; T39743; T39743.
DR RefSeq; NP_596721.1; NM_001022646.2.
DR AlphaFoldDB; Q9USY2; -.
DR SMR; Q9USY2; -.
DR BioGRID; 276175; 20.
DR STRING; 4896.SPBC1861.04c.1; -.
DR iPTMnet; Q9USY2; -.
DR MaxQB; Q9USY2; -.
DR PaxDb; Q9USY2; -.
DR PRIDE; Q9USY2; -.
DR EnsemblFungi; SPBC1861.04c.1; SPBC1861.04c.1:pep; SPBC1861.04c.
DR GeneID; 2539617; -.
DR KEGG; spo:SPBC1861.04c; -.
DR PomBase; SPBC1861.04c; -.
DR VEuPathDB; FungiDB:SPBC1861.04c; -.
DR eggNOG; KOG0128; Eukaryota.
DR HOGENOM; CLU_003925_0_0_1; -.
DR InParanoid; Q9USY2; -.
DR OMA; PSGLTKM; -.
DR PhylomeDB; Q9USY2; -.
DR Reactome; R-SPO-159236; Transport of Mature mRNA derived from an Intron-Containing Transcript.
DR Reactome; R-SPO-72165; mRNA Splicing - Minor Pathway.
DR Reactome; R-SPO-72187; mRNA 3'-end processing.
DR PRO; PR:Q9USY2; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016607; C:nuclear speck; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0005688; C:U6 snRNP; ISO:PomBase.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0017069; F:snRNA binding; ISO:PomBase.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:0000245; P:spliceosomal complex assembly; ISO:PomBase.
DR GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; ISO:PomBase.
DR CDD; cd12296; RRM1_Prp24; 1.
DR CDD; cd12297; RRM2_Prp24; 1.
DR CDD; cd12299; RRM4_Prp24; 1.
DR Gene3D; 1.25.40.10; -; 2.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR008669; LSM_interact.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR034397; Prp24_RRM1.
DR InterPro; IPR034398; Prp24_RRM2.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR031766; RRM_occluded.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF05391; Lsm_interact; 1.
DR Pfam; PF00076; RRM_1; 3.
DR Pfam; PF16842; RRM_occluded; 1.
DR SMART; SM00386; HAT; 3.
DR SMART; SM00360; RRM; 4.
DR SUPFAM; SSF48452; SSF48452; 1.
DR SUPFAM; SSF54928; SSF54928; 3.
DR PROSITE; PS50102; RRM; 4.
PE 4: Predicted;
KW Nucleus; Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..1014
FT /note="Uncharacterized RNA-binding protein C1861.04c"
FT /id="PRO_0000310819"
FT REPEAT 57..89
FT /note="HAT 1"
FT REPEAT 95..126
FT /note="HAT 2"
FT REPEAT 148..180
FT /note="HAT 3"
FT REPEAT 286..318
FT /note="HAT 4"
FT REPEAT 442..474
FT /note="HAT 5"
FT DOMAIN 590..667
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 666..743
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 757..832
FT /note="RRM 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 874..946
FT /note="RRM 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 953..1006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..580
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..985
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 986..1006
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1014 AA; 118008 MW; 45E15A7435EB08CF CRC64;
MSQIQDLKDE NVEMDIDPQE QNEKKPLLLD ELTKFTILHP YNYDSHIKLI EELKRLDKKK
ELSEARKTFQ SIFPLSEDLW VDYLLDECKN CRTLDDYVRI KTLFDLAVQD YLSIKIWCMY
LEFTLNLMDT SSFEQEQSEL NGVITLTDAH SLFERAYQTC KFHFSKSQCV WTLYLEFLQT
FGDALFEGEE EQEIVFKNKI YDFHIDRLKL PHEQIEETFT SLSTFVTNNW SPSEYEDVMV
KSNKVYETTL KRNAKIFNKE LLLNSANHSL EAYMDLINDE SRRSTAELQY ITTLYERAIV
LYPLIPELWL QYTAWLSKVD FSSSQASSVA ERATRNCSWI GRIWSIKLTY MTLSGASTSA
VCEEKDRCLN SNLLVNFDEV IDFFSGFLKA CLYLSSNEDK PQEFLKHQIH KVEDYLRKNH
KGSKDARMRI ELSKIYLYSE ISDFESVEKC WSDMFHDFQN QALYWISRYI STMKYNPELA
AETLKKSLYK NVDQPQLLFQ FYQSIMDLNN DCFTNTSHLY DVLNAQRISF KRQLDSFAEE
TKQTVENTEP LKVPQADDTA ALSKKRKPGQ EGDVFKKSKP IEQHRNREEL TVLVTNLPSD
ISENELKIFF KDCGNIIRIF ILEDNQKDVK VAQIEFSETS EVLAAKTRDL KSIRGHEISV
QIHVDTNLYV TNFPPTYDEL DITKLFSAYG NVVDVRFPSL RYNTNRRFCY VQMRKPDEAH
NALQLHKKLL EEKYPIQVFI SDPLRRTPRS GAVYEGRELY VTNIDFKVNE KDVETFFRDY
GQVESVRIPK RFNQHKGFGY VVMTTNQDAE NALSAAGKQL GNRVLNVVLS KPRESLEKTR
VSSNDNRTLA KSFETTESNK MSTPKKSFEQ IKSKSLGVTN VDGTVNEARL RSLFESYGKL
YRVVLHPEHE GAVVEFLDIH DAGKASLALE GHEIGGRLLH ITTVNEMMHN VPSSMNHSDY
NTSATRPRRL GSRTFQGFNS NHSNINSKKD DLDDKEMQID APKSNDDFRK MFLK
