ID   YP010_YEAST             Reviewed;          72 AA.
AC   A5Z2X5; D6W422;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=UPF0495 protein YPR010C-A {ECO:0000305};
GN   OrderedLocusNames=YPR010C-A {ECO:0000312|SGD:S000122558};
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169875;
RA   Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA   Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA   Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA   Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA   DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA   Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA   Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA   Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA   Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA   Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA   Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA   Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA   Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA   Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA   Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA   Vo D.H., Hani J.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL   Nature 387:103-105(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=17101987; DOI=10.1073/pnas.0605645103;
RA   Miura F., Kawaguchi N., Sese J., Toyoda A., Hattori M., Morishita S.,
RA   Ito T.;
RT   "A large-scale full-length cDNA analysis to explore the budding yeast
RT   transcriptome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:17846-17851(2006).
RN   [4]
RP   SUBCELLULAR LOCATION.
RX   PubMed=26928762; DOI=10.1038/nmeth.3795;
RA   Yofe I., Weill U., Meurer M., Chuartzman S., Zalckvar E., Goldman O.,
RA   Ben-Dor S., Schuetze C., Wiedemann N., Knop M., Khmelinskii A.,
RA   Schuldiner M.;
RT   "One library to make them all: streamlining the creation of yeast libraries
RT   via a SWAp-Tag strategy.";
RL   Nat. Methods 13:371-378(2016).
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=29897761; DOI=10.1021/acs.jproteome.8b00032;
RA   He C., Jia C., Zhang Y., Xu P.;
RT   "Enrichment-based proteogenomics identifies microproteins, missing
RT   proteins, and novel smORFs in Saccharomyces cerevisiae.";
RL   J. Proteome Res. 17:2335-2344(2018).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:26928762}. Membrane
CC       {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the UPF0495 family. {ECO:0000305}.
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DR   EMBL; Z49919; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BK006949; DAA11438.1; -; Genomic_DNA.
DR   RefSeq; NP_001091638.1; NM_001184689.1.
DR   AlphaFoldDB; A5Z2X5; -.
DR   BioGRID; 624549; 9.
DR   IntAct; A5Z2X5; 8.
DR   MINT; A5Z2X5; -.
DR   STRING; 4932.YPR010C-A; -.
DR   MaxQB; A5Z2X5; -.
DR   PaxDb; A5Z2X5; -.
DR   PRIDE; A5Z2X5; -.
DR   EnsemblFungi; YPR010C-A_mRNA; YPR010C-A; YPR010C-A.
DR   GeneID; 5142379; -.
DR   KEGG; sce:YPR010C-A; -.
DR   SGD; S000122558; YPR010C-A.
DR   VEuPathDB; FungiDB:YPR010C-A; -.
DR   eggNOG; ENOG502S6WH; Eukaryota.
DR   HOGENOM; CLU_180937_0_0_1; -.
DR   InParanoid; A5Z2X5; -.
DR   OMA; TYKKFAY; -.
DR   BioCyc; YEAST:G3O-34371-MON; -.
DR   PRO; PR:A5Z2X5; -.
DR   Proteomes; UP000002311; Chromosome XVI.
DR   RNAct; A5Z2X5; protein.
DR   GO; GO:0005829; C:cytosol; HDA:SGD.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Cytoplasm; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..72
FT                   /note="UPF0495 protein YPR010C-A"
FT                   /id="PRO_0000306772"
FT   TRANSMEM        20..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   72 AA;  7902 MW;  4CD3611175EBFCAD CRC64;
     MRPAQLLLNT AKKTSGGYKI PVELTPLFLA VGVALCSGTY FTYKKLRTDE TLRLTGNPEL
     SSLDEVLAKD KD