YP011_YEAST
ID YP011_YEAST Reviewed; 326 AA.
AC Q12251; D6W423;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 157.
DE RecName: Full=Uncharacterized mitochondrial carrier YPR011C;
GN OrderedLocusNames=YPR011C; ORFNames=LPZ11C, YP9531.04C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169875;
RA Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA Vo D.H., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL Nature 387:103-105(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RX PubMed=16823961; DOI=10.1021/pr050477f;
RA Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.;
RT "Toward the complete yeast mitochondrial proteome: multidimensional
RT separation techniques for mitochondrial proteomics.";
RL J. Proteome Res. 5:1543-1554(2006).
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16823961}; Multi-pass
CC membrane protein {ECO:0000269|PubMed:14562095,
CC ECO:0000269|PubMed:16823961}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; U31900; AAA97590.1; -; Genomic_DNA.
DR EMBL; Z49919; CAA90155.1; -; Genomic_DNA.
DR EMBL; Z71255; CAA95008.1; -; Genomic_DNA.
DR EMBL; BK006949; DAA11439.1; -; Genomic_DNA.
DR PIR; S57544; S57544.
DR RefSeq; NP_015336.1; NM_001184108.1.
DR AlphaFoldDB; Q12251; -.
DR SMR; Q12251; -.
DR BioGRID; 36190; 47.
DR DIP; DIP-1553N; -.
DR IntAct; Q12251; 1.
DR MINT; Q12251; -.
DR STRING; 4932.YPR011C; -.
DR TCDB; 2.A.29.23.9; the mitochondrial carrier (mc) family.
DR MaxQB; Q12251; -.
DR PaxDb; Q12251; -.
DR PRIDE; Q12251; -.
DR EnsemblFungi; YPR011C_mRNA; YPR011C; YPR011C.
DR GeneID; 856121; -.
DR KEGG; sce:YPR011C; -.
DR SGD; S000006215; YPR011C.
DR VEuPathDB; FungiDB:YPR011C; -.
DR eggNOG; KOG0752; Eukaryota.
DR HOGENOM; CLU_015166_10_1_1; -.
DR InParanoid; Q12251; -.
DR OMA; KLPGMWA; -.
DR BioCyc; YEAST:G3O-34173-MON; -.
DR PRO; PR:Q12251; -.
DR Proteomes; UP000002311; Chromosome XVI.
DR RNAct; Q12251; protein.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; ISM:SGD.
DR GO; GO:0005739; C:mitochondrion; HDA:SGD.
DR GO; GO:0046964; F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity; IDA:SGD.
DR GO; GO:1902557; F:5'-adenylyl sulfate transmembrane transporter activity; IDA:SGD.
DR GO; GO:1902559; P:3'-phospho-5'-adenylyl sulfate transmembrane transport; IDA:SGD.
DR GO; GO:1902558; P:5'-adenylyl sulfate transmembrane transport; IDA:SGD.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 1: Evidence at protein level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..326
FT /note="Uncharacterized mitochondrial carrier YPR011C"
FT /id="PRO_0000243949"
FT TRANSMEM 24..40
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 126..143
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 195..213
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..254
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 297..316
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 20..107
FT /note="Solcar 1"
FT REPEAT 120..219
FT /note="Solcar 2"
FT REPEAT 231..322
FT /note="Solcar 3"
SQ SEQUENCE 326 AA; 35913 MW; 317D4CD8041F4A21 CRC64;
MAEVLTVLEQ PNSIKDFLKQ DSNIAFLAGG VAGAVSRTVV SPFERVKILL QVQSSTTSYN
RGIFSSIRQV YHEEGTKGLF RGNGLNCIRI FPYSAVQFVV YEACKKKLFH VNGNNGQEQL
TNTQRLFSGA LCGGCSVVAT YPLDLIKTRL SIQTANLSSL NRSKAKSISK PPGIWQLLSE
TYRLEGGLRG LYRGVWPTSL GVVPYVALNF AVYEQLREFG VNSSDAQPSW KSNLYKLTIG
AISGGVAQTI TYPFDLLRRR FQVLAMGGNE LGFRYTSVWD ALVTIGRAEG VSGYYKGLAA
NLFKVVPSTA VSWLVYEVVC DSVRNW
