YP015_YEAST
ID YP015_YEAST Reviewed; 247 AA.
AC Q12531; D6W425; Q6Q5F4;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=Zinc finger protein YPR015C;
GN OrderedLocusNames=YPR015C; ORFNames=LPZ14c;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169875;
RA Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA Vo D.H., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL Nature 387:103-105(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP DOMAIN.
RX PubMed=9171100; DOI=10.1093/nar/25.12.2464;
RA Boehm S., Frishman D., Mewes H.-W.;
RT "Variations of the C2H2 zinc finger motif in the yeast genome and
RT classification of yeast zinc finger proteins.";
RL Nucleic Acids Res. 25:2464-2469(1997).
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DR EMBL; U31900; AAA97593.1; -; Genomic_DNA.
DR EMBL; Z49919; CAA90159.1; -; Genomic_DNA.
DR EMBL; Z71255; CAA95011.1; -; Genomic_DNA.
DR EMBL; AY558141; AAS56467.1; -; Genomic_DNA.
DR EMBL; BK006949; DAA11441.1; -; Genomic_DNA.
DR PIR; S57548; S57548.
DR RefSeq; NP_015340.1; NM_001184112.1.
DR AlphaFoldDB; Q12531; -.
DR SMR; Q12531; -.
DR BioGRID; 36192; 64.
DR DIP; DIP-6487N; -.
DR IntAct; Q12531; 11.
DR MINT; Q12531; -.
DR STRING; 4932.YPR015C; -.
DR PaxDb; Q12531; -.
DR PRIDE; Q12531; -.
DR EnsemblFungi; YPR015C_mRNA; YPR015C; YPR015C.
DR GeneID; 856125; -.
DR KEGG; sce:YPR015C; -.
DR SGD; S000006219; YPR015C.
DR VEuPathDB; FungiDB:YPR015C; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000176618; -.
DR HOGENOM; CLU_1116285_0_0_1; -.
DR InParanoid; Q12531; -.
DR OMA; PCSSIMH; -.
DR BioCyc; YEAST:G3O-34175-MON; -.
DR PRO; PR:Q12531; -.
DR Proteomes; UP000002311; Chromosome XVI.
DR RNAct; Q12531; protein.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR Pfam; PF00096; zf-C2H2; 2.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 4: Predicted;
KW Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger.
FT CHAIN 1..247
FT /note="Zinc finger protein YPR015C"
FT /id="PRO_0000255975"
FT ZN_FING 185..207
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 213..237
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT CONFLICT 184
FT /note="R -> W (in Ref. 3; AAS56467)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 247 AA; 27775 MW; 418504BA47B0C165 CRC64;
MWRTKTLESM LCSPMKCSSS NIGGSYAQSS KEVSNTTKRE VHLPPCSSIM HAPLTPEINQ
AALPPPAYHY APSSLHQTED PVWRSSPNSI IFSPVIATPQ PFPLTFVERQ SCCPIYSTAA
SSYTAQSVPP SMQHFQEENH RAVSNEQYSL PNVHIGQNPG TLLSQTQTDL DLIQKQLRAV
VKLRKQCPIC GKVCSRPSTL RTHYLIHTGD TPFKCTWEHC NKSFNVKSNM LRHLRTHQKK
IAKKKHQ
