YP02_SCHPO
ID YP02_SCHPO Reviewed; 386 AA.
AC Q9Y7Z6;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Meiotic chromosome segregation protein C1539.02;
GN ORFNames=SPBC1539.02;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION.
RX PubMed=16169489; DOI=10.1016/j.cub.2005.07.059;
RA Gregan J., Rabitsch P.K., Sakem B., Csutak O., Latypov V., Lehmann E.,
RA Kohli J., Nasmyth K.;
RT "Novel genes required for meiotic chromosome segregation are identified by
RT a high-throughput knockout screen in fission yeast.";
RL Curr. Biol. 15:1663-1669(2005).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Required for meiotic chromosome segregation.
CC {ECO:0000269|PubMed:16169489}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAB51334.1; -; Genomic_DNA.
DR PIR; T39461; T39461.
DR RefSeq; NP_596816.1; NM_001023836.2.
DR AlphaFoldDB; Q9Y7Z6; -.
DR SMR; Q9Y7Z6; -.
DR STRING; 4896.SPBC1539.02.1; -.
DR iPTMnet; Q9Y7Z6; -.
DR MaxQB; Q9Y7Z6; -.
DR PaxDb; Q9Y7Z6; -.
DR PRIDE; Q9Y7Z6; -.
DR EnsemblFungi; SPBC1539.02.1; SPBC1539.02.1:pep; SPBC1539.02.
DR GeneID; 2539927; -.
DR KEGG; spo:SPBC1539.02; -.
DR PomBase; SPBC1539.02; -.
DR VEuPathDB; FungiDB:SPBC1539.02; -.
DR eggNOG; KOG2498; Eukaryota.
DR HOGENOM; CLU_735999_0_0_1; -.
DR InParanoid; Q9Y7Z6; -.
DR OMA; NHEENTH; -.
DR PRO; PR:Q9Y7Z6; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR InterPro; IPR039896; Red-like.
DR InterPro; IPR012916; RED_N.
DR PANTHER; PTHR12765; PTHR12765; 2.
DR Pfam; PF07808; RED_N; 1.
PE 4: Predicted;
KW Cell cycle; Meiosis; Nucleus; Reference proteome.
FT CHAIN 1..386
FT /note="Meiotic chromosome segregation protein C1539.02"
FT /id="PRO_0000358936"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 46..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 386 AA; 44361 MW; C2F5FEC977EE6164 CRC64;
MNQDDFRKLL ATPKAETSQL KNFSSNKSQR LVFGRKHKTA KLEAPRALIK RKQLSHSTSS
DITRHSNAKN SGKDTQFYEE PSSKQDIELH KLHEKLRNGQ ITTKEYSEKS KELGGDLNTT
HLVRGLDRKL LEKVRSNELA LDDSLLSSSE KEVDEEADKL LEKVAEESSH PESVSILEEK
KKIPLYPNGQ PKYRKILENG KKVKYLLDEN GEILKRLVKK EKKLKNDNER LENEHRTEKL
NVNANSLGKS FVKHDIPLPP VDLKLDIFEE VGEYDPFHEN DKEPAELKAK DAFQLKGHHE
LDAPYHKKVF DTNQYSDLKP TNFMSQIHRL AKVQERKEEE ERKKGKDGQI VDAGFGLVLS
KDDTADIHEL GESDDDDNVK RRKTKG
