YP089_YEAST
ID YP089_YEAST Reviewed; 888 AA.
AC O13585; D6W490; Q86ZS6;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2004, sequence version 2.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=Dilute domain-containing protein YPR089W;
GN OrderedLocusNames=YPR089W; ORFNames=YPR090W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169875;
RA Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA Vo D.H., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL Nature 387:103-105(1997).
RN [2]
RP SEQUENCE REVISION.
RA Sethuraman A., Cherry J.M.;
RL Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 105-179.
RC STRAIN=S288c / YPH1;
RX PubMed=12844361; DOI=10.1186/gb-2003-4-7-r45;
RA Brachat S., Dietrich F.S., Voegeli S., Zhang Z., Stuart L., Lerch A.,
RA Gates K., Gaffney T.D., Philippsen P.;
RT "Reinvestigation of the Saccharomyces cerevisiae genome annotation by
RT comparison to the genome of a related fungus: Ashbya gossypii.";
RL Genome Biol. 4:R45.1-R45.13(2003).
RN [5]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [6]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 3690 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; U51033; AAB68146.2; -; Genomic_DNA.
DR EMBL; AY260887; AAP21755.1; -; Genomic_DNA.
DR EMBL; BK006949; DAA11506.1; -; Genomic_DNA.
DR PIR; S70046; S70046.
DR RefSeq; NP_015414.2; NM_001184186.1.
DR AlphaFoldDB; O13585; -.
DR SMR; O13585; -.
DR BioGRID; 36259; 253.
DR DIP; DIP-34618N; -.
DR IntAct; O13585; 14.
DR STRING; 4932.YPR089W; -.
DR iPTMnet; O13585; -.
DR MaxQB; O13585; -.
DR PaxDb; O13585; -.
DR PRIDE; O13585; -.
DR EnsemblFungi; YPR089W_mRNA; YPR089W; YPR089W.
DR GeneID; 856204; -.
DR KEGG; sce:YPR089W; -.
DR SGD; S000006293; YPR089W.
DR VEuPathDB; FungiDB:YPR089W; -.
DR eggNOG; ENOG502QRMC; Eukaryota.
DR HOGENOM; CLU_019651_0_0_1; -.
DR InParanoid; O13585; -.
DR BioCyc; YEAST:G3O-34232-MON; -.
DR PRO; PR:O13585; -.
DR Proteomes; UP000002311; Chromosome XVI.
DR RNAct; O13585; protein.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0051020; F:GTPase binding; IBA:GO_Central.
DR CDD; cd15473; Myo5p-like_CBD_DIL_ANK; 1.
DR Gene3D; 1.25.40.20; -; 1.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR037986; Myo5p-like_CBD_DIL.
DR Pfam; PF01843; DIL; 1.
DR SMART; SM01132; DIL; 1.
DR SUPFAM; SSF48403; SSF48403; 1.
DR PROSITE; PS51126; DILUTE; 1.
PE 1: Evidence at protein level;
KW Golgi apparatus; Reference proteome.
FT CHAIN 1..888
FT /note="Dilute domain-containing protein YPR089W"
FT /id="PRO_0000257825"
FT DOMAIN 360..745
FT /note="Dilute"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00503"
FT REGION 462..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 805..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 865..888
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..825
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 888 AA; 102579 MW; 3F1634E5B2093DE9 CRC64;
MNSVWDDARI EDRTVDKPVG SSHAQEKLAL VKSTLFKLDQ EDRPECDSWV QLVKLICDED
REEEFTTFKE LLREVKNVND KSVTGVALIH YIIVFDRADY IELLHDNPSG AKLDLNLVDD
IVGYTPLMWS FSLQRRNCCL ELFNAFDEIN FNMTNKAGLT AWDMVPPYSP LSEFLEQNNM
FRYRTEVKHE IPQISQPKDT SLLMSNEDST TKETFDNIDL QVAGLTLSPG ANDNMFLDSD
EKNMNHSQGA ATLIDPTYTE DYHGTFDYDK LSPDQYLEFS DFDIPQILNL LISLPQKEPH
MTTYPAGLIY QCIRYADHKI KSKPLVESLI NLSLTKILTS VSSNGAAGLV STEASLQAGD
IVLQSYWLSC LSFLYYYLCR DDSFFKRHPS VLQELINTIH SIIIELTSSI HCRLISLIDS
TLLAYTTIQD VKQTLYKRDW NFFKKRKQAK LLLKEKNRKQ LKEQQKKELH RKSQGQENHE
EEEGQQDGND SDDRASTNDD NNSSVSLFYD KEILRHLYPP SFEEQMKPSP LKIVQIFGAL
SYVLNLHQTH PIFQQQCLSI SVNWFATTLF NKILKDKKKR SLSRAHAIQI RLNLSTLESW
IQNNDFCVPK PMLIDDFMWQ RFPMTLIRDV GEIDLSDPIL RNVATYKPID ENNKDLIYDT
SNSLFYYQPF HKIAQIHLEP VFQLLQWLQV ATTLDSEESL ISTMNLLPRI TPVQLLKSME
KYNYELNENK FNSKLKKFLN NKIKDSKMSK ADAYLQEHEI PYLVLPTIPE MTDLYSKGPD
SHSFQPFLPG SIQDDVYEIH DVNFKQRQNE PQISRTNSGT SDFTGDEDKA QYETEGVGES
IDINETVEPE SNAFNVGNDD YFKELNIPSS TAQRPAWSNN DDMEQNPW
